Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184835 | 0.86 | GRN (0.49) | NPC1RAB9ACTDSP1PTGS2PIN1 | |
| SCHEMBL13482964 | 0.83 | NPC1 (0.47) | NPC1RAB9ACTDSP1PIN1GAA | |
| SCHEMBL3187487 | 0.78 | POLB (0.49) | NPC1RAB9ACTDSP1PTGS2PIN1 | |
| SCHEMBL5162493 | 0.78 | ACE (0.56) | PIN1CA1 | |
| SCHEMBL5162484 | 0.78 | ACE (0.56) | PIN1CA1 | |
| SCHEMBL25423794 | 0.76 | NPC1 (0.47) | NPC1RAB9ACTDSP1PTGS2PIN1 | |
| SCHEMBL5924980 | 0.74 | TSHR (0.50) | GAAPOLBKDM4EALOX15ALDH1A1 | |
| SCHEMBL5135522 | 0.73 | GGH (0.38) | PIN1TSHR | |
| SCHEMBL7372269 | 0.72 | TDP1 (0.55) | RAB9APTGS2PIN1GAACA1 | |
| SCHEMBL7387190 | 0.72 | TDP1 (0.55) | RAB9APTGS2PIN1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659424-B2 | Process for the allylation of n-acylhydrazones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20070142672-A1 | Process for the allylation of n-acylhydrazones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1721890-A1 | PROCESS FOR THE ALLYLATION OF N-ACYLHYDRAZONES | Japan Science and Technology Agency (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142672-A1 | Process for the allylation of n-acylhydrazones | HRH4, NAT1, CBR3 | NPC1 1646/4885RAB9A 3485/4885CTDSP1 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.