Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31824 | 0.92 | AURKA (0.66) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4313957 | 0.92 | AURKA (0.66) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4321146 | 0.91 | AURKA (0.63) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4321138 | 0.91 | AURKA (0.63) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL27691460 | 0.90 | AURKA (0.62) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4312987 | 0.90 | AURKA (0.62) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4312994 | 0.90 | AURKA (0.62) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4327023 | 0.88 | AURKA (0.58) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4327020 | 0.88 | AURKA (0.58) | AURKAAURKBNPC1RAB9AKMT2A | |
| SCHEMBL4313205 | 0.87 | AURKA (0.74) | AURKAAURKBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026511-A1 | PHARMACEUTICAL COMPOSITION | 協和発酵キリン株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |