Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195570 | 0.88 | TP53 (0.56) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3186400 | 0.85 | TSHR (0.60) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3179914 | 0.84 | TP53 (0.71) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3188506 | 0.84 | MAPT (0.58) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3186204 | 0.84 | TSHR (0.78) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3198511 | 0.84 | MAPT (0.56) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3191805 | 0.84 | TSHR (0.69) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3179798 | 0.83 | MAPT (0.59) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3201387 | 0.83 | TP53 (0.55) | ALDH1A1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL3191319 | 0.80 | TSHR (0.54) | ALDH1A1KMT2ATSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671069-B2 | Tricyclic, heteroaromatic compounds modulating CXCR4 and/ or CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20070254915-A1 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254915-A1 | CXCR4 MODULATORS | CXCL12, CXCR4, CXCR1 | ALDH1A1 662/4885KMT2A 3838/4885TSHR 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.