Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 7/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911223 | 1.00 | FUCA1 (0.42) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL319229 | 0.89 | FUCA1 (0.39) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL10278488 | 0.89 | FUCA1 (0.39) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL1911252 | 0.88 | FUCA1 (0.38) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL319110 | 0.88 | FUCA1 (0.38) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL1911145 | 0.88 | FUCA1 (0.38) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL1911139 | 0.87 | FUCA1 (0.36) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL1910730 | 0.87 | FUCA1 (0.36) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL12503269 | 0.87 | FUCA1 (0.36) | FUCA1KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL320692 | 0.83 | KDM1A (0.33) | FUCA1KDM1AMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590968-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | Novartis AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |