Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646991 | 0.87 | KMT2A (0.47) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL4645745 | 0.85 | KMT2A (0.46) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL689958 | 0.85 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL4644726 | 0.83 | GAA (0.48) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL688230 | 0.83 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL688760 | 0.83 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL688269 | 0.81 | GAA (0.54) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL20565454 | 0.81 | PRSS1 (0.50) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL4644742 | 0.79 | GAA (0.48) | KMT2AKDM4EMEN1RECQLGAA | |
| SCHEMBL1246062 | 0.79 | MEN1 (0.67) | KMT2AKDM4EMEN1RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089440-B1 | RADICALLY CURABLE COMPOSITION CONTAINING POLYMERIZABLE MONOMER AND RADICAL FORMER | SIKA TECHNOLOGY AG (CH) | 2013-12-18 | — | — | EP | claimed |
| US-20100028701-A1 | Free-radically curable composition comprising polymerizable monomer and free-radical initiator | SIKA TECHNOLOGY AG (CH) | 2010-02-04 | — | — | US | disclosed |