SCHEMBL3194293

SCHEMBL3194293

Fc1ccc(-c2n[nH]c(-c3ccccn3)n2)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.61
RAB9A P51151 3/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
ALPL P05186 1/20 0.61
PKM P14618 1/20 0.61
ALOX15 P16050 1/20 0.61
HSD17B10 Q99714 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
KDM4E B2RXH2 1/20 0.55
NOTUM Q6P988 1/20 0.52
CBFB Q13951 3/20 0.49
METAP2 P50579 1/20 0.49
METAP1 P53582 1/20 0.49
NPY5R Q15761 1/20 0.44
F2 P00734 1/20 0.43
F12 P00748 1/20 0.43
PLAU P00749 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17077595 0.81 NPC1 (0.45) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL27931261 0.81 NPC1 (0.45) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL17077592 0.80 NPC1 (0.44) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL27910618 0.80 NPC1 (0.44) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL28864794 0.80 NPC1 (0.44) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL2791438 0.80 NPC1 (0.77) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL31036229 0.79 MEN1 (0.51) NPC1RAB9AL3MBTL1KDM4ECBFB
SCHEMBL2789192 0.79 NPC1 (0.70) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL514547 0.77 MEN1 (0.52) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL
SCHEMBL8311588 0.77 SMN1; SMN2 (1.00) NPC1RAB9AL3MBTL1SMN1; SMN2ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662486-B2 blue phosphorescent AU OPTRONICS CORP. (TW) 2010-02-16 US disclosed
US-7662486-B2 blue phosphorescent AU OPTRONICS CORP. (TW) 2010-02-16 US disclosed
US-7662486-B2 blue phosphorescent AU OPTRONICS CORP. (TW) 2010-02-16 US disclosed
CN-100503771-C Light-emitting material and organic electroluminescent module using the same AU OPTRONICS CORP (CN) 2009-06-24 CN disclosed
US-20060286404-A1 Light emission material and organic electroluminescent device using the same AU OPTRONICS CORP. (TW) 2006-12-21 US disclosed
CN-1696243-A Light-emitting material and organic electroluminescent module using the same YOUDA PHOTOELECTRIC CO LTD (CN) 2005-11-16 CN disclosed