SCHEMBL3194473

SCHEMBL3194473

CCNc1cccc(C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
RECQL P46063 1/20 0.50
TRPA1 O75762 2/20 0.46
IDO1 P14902 2/20 0.44
MAPT P10636 3/20 0.43
HTT P42858 2/20 0.43
HSD17B10 Q99714 2/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
USP2 O75604 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29118509 0.81 HTT (0.47) ALDH1A1CYP3A4RECQLTRPA1IDO1
SCHEMBL4624627 0.81 IDO1 (0.50) ALDH1A1CYP3A4TSHRRECQLTRPA1
SCHEMBL21333978 0.81 CYP3A4 (0.57) ALDH1A1CYP3A4TSHRRECQLTRPA1
SCHEMBL4050173 0.80 MAPT (0.50) ALDH1A1TSHRTRPA1MAPTHTT
Hydrochloric Acid SCHEMBL25292962 0.79 IDO1 (0.48) ALDH1A1CYP3A4TSHRRECQLTRPA1
SCHEMBL1122539 0.78 MAPT (0.53) ALDH1A1CYP3A4TSHRRECQLTRPA1
SCHEMBL29512292 0.78 MAPT (0.70) ALDH1A1CYP3A4TSHRRECQLIDO1
SCHEMBL442009 0.78 MAPT (0.70) ALDH1A1CYP3A4TSHRRECQLIDO1
SCHEMBL29512293 0.78 MAPT (0.70) ALDH1A1CYP3A4TSHRRECQLIDO1
SCHEMBL8446926 0.78 IDO1 (0.43) ALDH1A1CYP3A4TSHRRECQLIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117180247-B Application of 2-amino-6-methylphenol derivative as iron death inhibitor in preparation of medicines for preventing and treating osteoarthritis The First Affiliated Hospital of Shandong First Medical University (CN) 2026-05-26 CN disclosed
CN-117180247-A Application of 2-amino-6-methylphenol derivative as iron death inhibitor in preparation of medicines for preventing and treating osteoarthritis 山东第一医科大学第一附属医院(山东省千佛山医院) 2023-12-08 CN disclosed
CN-113613732-A Liquid hair dye composition 花王株式会社 2021-11-05 CN disclosed
EP-2964624-B1 RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LTD (GB) 2017-01-04 EP disclosed
EP-2964624-A1 RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS Illumina Cambridge Limited (GB) 2016-01-13 EP disclosed
US-9222131-B2 Rhodamine compounds and their use as fluorescent labels ILLUMINA CAMBRIDGE LIMITED 2015-12-29 US disclosed
WO-2014135223-A1 RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LTD (GB) 2014-09-12 WO disclosed
US-20140255920-A1 RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LIMITED (GB) 2014-09-11 US disclosed
US-8754244-B1 Rhodamine compounds and their use as fluorescent labels ILLUMINA CAMBRIDGE LIMITED (GB) 2014-06-17 US disclosed
US-8455413-B2 Additive for oils and lubricant comprising the same KH NEOCHEM CO., LTD. (JP) 2013-06-04 US disclosed
US-20100298183-A1 ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME KYOWA HAKKO CHEMICAL CO., LTD. (JP) 2010-11-25 US disclosed
US-20100031453-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT L'OREAL S.A. (FR) 2010-02-11 US disclosed
EP-2032540-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT L'Oreal (FR) 2009-03-11 EP disclosed
WO-2008034650-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT L'OREAL (FR) 2008-03-27 WO disclosed
EP-0167998-B1 RHODAMINE DYESTUFFS BASF Aktiengesellschaft (DE) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298183-A1 ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME NCOA2, NCOR2, NR1H2 ALDH1A1 1728/4885CYP3A4 1302/4885TSHR 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.