Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3194485 | 1.00 | MAPT (0.48) | MAPTABCC4LMNAUSP2RECQL | |
| Acetic Acid SCHEMBL28522340 | 0.94 | MAPT (0.57) | MAPTABCC4LMNAUSP2RECQL | |
| Acetic Acid SCHEMBL28514189 | 0.94 | MAPT (0.57) | MAPTABCC4LMNAUSP2RECQL | |
| Propionic Acid SCHEMBL21080966 | 0.88 | MAPT (0.50) | MAPTABCC4LMNAUSP2RECQL | |
| Propionic Acid SCHEMBL21080968 | 0.88 | MAPT (0.50) | MAPTABCC4LMNAUSP2RECQL | |
| SCHEMBL22094 | 0.86 | — | — | |
| SCHEMBL6474826 | 0.86 | — | — | |
| SCHEMBL22093 | 0.86 | — | — | |
| SCHEMBL25185257 | 0.84 | TSHR (0.46) | MAPTABCC4LMNAUSP2RECQL | |
| SCHEMBL1535152 | 0.84 | TSHR (0.46) | MAPTABCC4LMNAUSP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100115708-A1 | Laundry System Having Unitized Dosing | CASWELL DEBRA SUE | 2010-05-13 | — | — | US | disclosed |
| US-20100035789-A1 | Laundry System Having Unitized Dosing | CASWELL DEBRA SUE | 2010-02-11 | — | — | US | disclosed |
| US-7544651-B2 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY (US) | 2009-06-09 | — | — | US | disclosed |
| US-7534758-B2 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-19 | — | — | US | disclosed |
| US-20090062173-A1 | Laundry System Having Unitized Dosing | CASWELL DEBRA SUE | 2009-03-05 | — | — | US | disclosed |
| US-7494965-B2 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080009432-A1 | Laundry system having unitized dosing | CASWELL DEBRA S | 2008-01-10 | — | — | US | disclosed |
| US-20070111918-A1 | Laundry system having unitized dosing | CASWELL DEBRA S | 2007-05-17 | — | — | US | disclosed |
| US-7186680-B2 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-06 | — | — | US | disclosed |
| US-7166565-B2 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY (US) | 2007-01-23 | — | — | US | disclosed |
| US-20060168739-A1 | HIGHLY CONCENTRATED FABRIC SOFTENER COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOSITIONS | CASWELL DEBRA S | 2006-08-03 | — | — | US | disclosed |
| US-20060123556-A1 | Laundry system having unitized dosing | CASWELL DEBRA S | 2006-06-15 | — | — | US | disclosed |
| US-20060123557-A1 | Laundry system having unitized dosing | CASWELL DEBRA S | 2006-06-15 | — | — | US | disclosed |
| US-20050250670-A1 | Highly concentrated fabric softener compositions and articles containing such compositions | CASWELL DEBRA S | 2005-11-10 | — | — | US | disclosed |
| US-6958313-B2 | Highly concentrated fabric softener compositions and articles containing such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-25 | — | — | US | disclosed |
| US-20050202990-A1 | Laundry system having unitized dosing | THE PROCTER & GAMBLE COMPANY | 2005-09-15 | — | — | US | disclosed |
| US-20050176611-A1 | Laundry system having unitized dosing | CASWELL DEBRA S (CN) | 2005-08-11 | — | — | US | disclosed |
| US-20050079993-A1 | Highly concentrated fabric softener compositions and articles containing such compositions | THE PROCTER & GAMBLE COMPANY CORPORATION | 2005-04-14 | — | — | US | disclosed |
| US-6451065-B2 | CONTACTING WITH A MIXTURE OF PERFUME, A METALLIC SALT, SUCH AS ZINC CHLORIDE, AN OPTIONAL SOLUBILIZER, AND AQUEOUS CARRIER; DOES NOT SOIL OR STAIN FABRIC | THE PROCTER & GAMBLE COMPANY | 2002-09-17 | — | — | US | disclosed |
| CN-1215048-A | Vitamin A related compounds and methods for their production | SUMITOMO CHEMICAL CO (JP) | 1999-04-28 | — | — | CN | disclosed |