SCHEMBL319465

SCHEMBL319465

Oc1cccc2ccc3cccnc3c12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
MMP2 P08253 2/20 0.70
METAP2 P50579 2/20 0.70
CHRM1 P11229 1/20 0.70
COMT P21964 1/20 0.70
ADRA1A P35348 1/20 0.70
METAP1 P53582 1/20 0.70
HDAC8 Q9BY41 1/20 0.70
KDM4E B2RXH2 5/20 0.59
ALOX12 P18054 3/20 0.59
LMNA P02545 5/20 0.58
MAPT P10636 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
NFKB1 P19838 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
TP53 P04637 2/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58
CCR1 P32246 2/20 0.58
CCR5 P51681 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596497 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
Hydrochloric Acid SCHEMBL28885463 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL29689506 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL29349897 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL1927903 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL31674409 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL28374647 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL1573098 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL5492505 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT
SCHEMBL30171047 0.98 TSHR (0.68) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3100 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102751-B Gel polymer electrolyte membrane for lithium isotope separation and preparation method and application thereof 中国科学院青海盐湖研究所 2025-03-18 CN claimed
CN-119490453-A Synthesis method of 10-hydroxybenzo [ H ] quinoline 山西义诺新材料技术有限公司 2025-02-21 CN claimed
CN-118126022-B Near infrared ratio type fluorescent probe and preparation method and application thereof 江苏蒙博生物工程科技有限公司 2024-11-15 CN claimed
CN-118164954-B Fluorescent probe based on 10-hydroxybenzo [ h ] quinoline fluorescent parent nucleus, preparation method and application 江苏蒙博生物工程科技有限公司 2024-09-27 CN claimed
CN-118566189-A Method for quantitatively detecting protein based on double-emission-ratio fluorescent sensor 四川大学 2024-08-30 CN claimed
CN-118464859-A LnMOFs-ratio fluorescence sensor functionalized by 10-hydroxybenzo [ h ] quinoline and preparation method and application thereof 四川大学 2024-08-09 CN claimed
CN-118164954-A Fluorescent probe based on 10-hydroxybenzo [ h ] quinoline fluorescent parent nucleus, preparation method and application 江苏蒙博生物工程科技有限公司 2024-06-11 CN claimed
CN-118126022-A Near infrared ratio type fluorescent probe and preparation method and application thereof 江苏蒙博生物工程科技有限公司 2024-06-04 CN claimed
US-11706946-B2 Stretchable display device ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2023-07-18 US claimed
CN-116102751-A Gel polymer electrolyte membrane for lithium isotope separation and preparation method and application thereof 中国科学院青海盐湖研究所 2023-05-12 CN claimed
US-7517470-B2 Organic-inorganic hybrid material, composition for synthesizing the same, and manufacturing method of the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-14 US claimed
US-7232616-B2 Organic electroluminescent materials and devices made from such materials TSINGHUA UNIVERSITY (CN) 2007-06-19 US claimed
US-20060247124-A1 Polymerisation reaction and catalyst therefor JOHNSON MATTHEY PLC (GB) 2006-11-02 US claimed
EP-1569996-A1 POLYMERISATION REACTION AND CATALYST THEREFOR JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2005-09-07 EP claimed
WO-2004052980-A1 POLYMERISATION REACTION AND CATALYST THEREFOR JOHNSON MATTHEY PLC (GB) 2004-06-24 WO claimed
US-20040001970-A1 Organic electroluminescent materials and devices made from such materials TSINGHUA UNIVERSITY (CN) 2004-01-01 US claimed
US-6660411-B2 Can emit light at a low voltage and a high efficiency and can be driven in a stable manner MITSUBISHI CHEMICAL CORPORATION (JP) 2003-12-09 US claimed
WO-2003018662-A1 CATALYSTS AND CURABLE COMPOSITIONS JOHNSON MATTHEY PLC (GB) 2003-03-06 WO claimed
US-20020055015-A1 Organic electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2002-05-09 US claimed
EP-0502964-B1 USE OF COMPLEX LIGANDS FOR IONS IN FERROELECTRIC LIQUID CRYSTAL MIXTURES HOECHST AG (DE) 1995-02-22 EP claimed