Fructose

Fructose

SCHEMBL3196299

N.O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
PDE4A P27815 1/20 0.50
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
KDM4E B2RXH2 2/20 0.34
OR51E2 Q9H255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fructose SCHEMBL27619943 1.00 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL6262755 1.00 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL15993990 0.98 CYP2C9 (0.54) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL16944031 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL20898472 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Tagatose SCHEMBL23827342 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL21114385 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Tagatose SCHEMBL21816881 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Tagatose SCHEMBL4035 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL2123235 0.97 CYP2C9 (0.58) CYP2C9TSHRPDE4ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106574926-B For predicting the biomarker of weight degree of alleviation 雀巢产品技术援助有限公司 2019-04-19 CN claimed
CN-109072302-A non-invasive diagnosis of non-alcoholic steatohepatitis 基恩菲特公司 2018-12-21 CN claimed
CN-108697769-A Glucagon for treating obesity and GLP-1 co-agonists 免疫医疗有限公司 2018-10-23 CN claimed
CN-108138232-A For diagnosing and assessing the method for nonalcoholic fatty liver disease 基恩菲特公司 2018-06-08 CN claimed
CN-108026529-A Combination treatment IONIS制药公司 2018-05-11 CN claimed
CN-107638562-A The quick foundation and/or termination of basic steady-state drug delivery 精达制药公司 2018-01-30 CN claimed
CN-107108710-A Modified FGF-21 polypeptides and uses thereof 百时美施贵宝公司 2017-08-29 CN claimed
EP-2863934-B1 ADVANCED GLYCATION END PRODUCT ANALOGUES PHYTOQUEST LTD (GB) 2017-08-16 EP claimed
CN-106574926-A Biomarkers for predicting degree of weight loss 雀巢产品技术援助有限公司 2017-04-19 CN claimed
WO-2016036944-A1 TRANSDERMAL ANALYTE MONITORING SYSTEMS CORRECTED FOR ON-SKIN AND BREAK-IN CURRENTS ECHO THERAPEUTICS, INC. (US) 2016-03-10 WO claimed
CN-101505746-A Treatment of inflammatory conditions DYNAMIS THERAPEUTICS INC (US) 2009-08-12 CN claimed
CN-101084235-A 3-deoxyglucosone and skin DYNAMIS THERAPEUTICS INC (US) 2007-12-05 CN claimed
US-6503198-B1 Noninvasive transdermal systems for detecting an analyte obtained from or underneath skin and methods ARONOWITZ, JACK L. 2003-01-07 US claimed
JP-1108997-A None JP disclosed
JP-1108997-A None JP disclosed
CN-110366426-A A method of promoting insulin secretion 泰伦基国际有限公司 2019-10-22 CN disclosed
US-5736400-A Method for modifying, diagnosing and screening for IGF-I sensitive cell barriers MOSES ALAN C (US) 1998-04-07 US disclosed
US-5637567-A EXPOSURE TO SOMATOMEDINS THE BETH ISRAEL HOSPITAL ASSOCIATION (US) 1997-06-10 US disclosed
JP-H01108997-A SPECIFIC DETERMINATION OF FRUCTOSE AMINE CONTENT IN SERUM IN BLOOD OR SPECIMEN DERIVED FROM BLOOD, AND REMOVAL OF COMPONENT HAVING NON SPECIFIC REDUCING ACTION AND/OR CAUSING TURBIDITY IN SPECIMEN BOEHRINGER MANNHEIM GMBH 1989-04-26 JP disclosed
JP-H01108997-A SPECIFIC DETERMINATION OF FRUCTOSE AMINE CONTENT IN SERUM IN BLOOD OR SPECIMEN DERIVED FROM BLOOD, AND REMOVAL OF COMPONENT HAVING NON SPECIFIC REDUCING ACTION AND/OR CAUSING TURBIDITY IN SPECIMEN BOEHRINGER MANNHEIM GMBH 1989-04-26 JP disclosed