Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | PHGDH | O43175 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413213 | 1.00 | NR1H4 (0.59) | NR1H4CNR1NPC1PTGER4PTGER2 | |
| SCHEMBL22499610 | 0.84 | MEN1 (0.58) | NPC1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL14040888 | 0.84 | MEN1 (0.58) | NPC1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL5219016 | 0.84 | MEN1 (0.58) | NPC1HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL4511424 | 0.84 | CNR1 (0.51) | NR1H4CNR1NPC1KMT2AACACB | |
| SCHEMBL21932297 | 0.84 | CNR1 (0.51) | NR1H4CNR1NPC1KMT2AACACB | |
| SCHEMBL21932490 | 0.84 | CNR1 (0.51) | NR1H4CNR1NPC1KMT2AACACB | |
| SCHEMBL21399858 | 0.83 | CNR1 (0.49) | NR1H4CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL3652541 | 0.82 | NR1H4 (0.61) | NR1H4NPC1PTGER4PTGER2PHGDH | |
| SCHEMBL958778 | 0.81 | SMN1; SMN2 (0.55) | CNR1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-111132972-A | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-RE46683-E1 | Nucleic acid terminators incorporating a cationic moiety and methods for their use | APPLIED BIOSYSTEMS, LLC (US) | 2018-01-23 | — | — | US | disclosed |
| US-8389699-B2 | Nucleic acid terminators incorporating a cationic moiety and methods for their use | APPLIED BIOSYSTEMS, LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100035326-A1 | Nucleic Acid Terminators Incorporating a Cationic Moiety and Methods for Their Use | Life Technologies Corporation (US) | 2010-02-11 | — | — | US | disclosed |