Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811312 | 1.00 | FFAR1 (0.56) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL24450560 | 0.96 | FFAR1 (0.60) | FFAR1FFAR4FAAHTRPV1GPR84 | |
| SCHEMBL2933857 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL1070641 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL17743910 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL2826342 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL17744144 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL10081525 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH | |
| SCHEMBL811332 | 0.93 | FFAR1 (0.57) | FFAR1FFAR4FAAHTRPV1GPR84 | |
| SCHEMBL6008572 | 0.93 | FFAR1 (0.62) | FFAR1FFAR4F7F3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207313-B2 | Natural products from Vinca | WILLIAM MARSH RICE UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |
| US-20100048494-A1 | Natural Products from Vinca | RICE UNIVERSITY (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2008101238-A2 | NATURAL PRODUCTS FROM VINCA | RICE UNIVERSITY (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048494-A1 | Natural Products from Vinca | HIRA, RDX, SLC22A8 | FFAR1 3698/4885FFAR4 4057/4885F7 4045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.