⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351081 | 1.00 | — | — | |
| SCHEMBL492073 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29131455 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2346747 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2349412 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1090593 | 0.97 | — | — | |
| SCHEMBL22732393 | 0.82 | — | — | |
| SCHEMBL3207004 | 0.82 | — | — | |
| SCHEMBL2148328 | 0.69 | — | — | |
| SCHEMBL4279010 | 0.67 | SLC18A3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142428-A1 | Isoquinoline-3-carboxylic acid amides and pharmaceutical uses thereof | NOVARTIS AG (CH) | 2007-06-21 | — | — | US | claimed |
| CN-115703777-B | Separation method of 3-quinuclidinone | 上海医药工业研究院 | 2025-03-21 | — | — | CN | disclosed |
| US-10611793-B1 | Solid state forms of obeticholic acid salts | TEVA CZECH INDUSTRIES S.R.O. (CZ) | 2020-04-07 | — | — | US | disclosed |
| EP-3016642-A1 | METHOD FOR PREVENTING AND/OR TREATING CHRONIC TRAUMATIC ENCEPHALOPATHY-I | Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) (AU) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015000032-A1 | METHOD FOR PREVENTING AND/OR TREATING CHRONIC TRAUMATIC ENCEPHALOPATHY-I | EUSTRALIS PHARMACEUTICALS LIMITED (TRADING AS PRESSURA NEURO) (AU) | 2015-01-08 | — | — | WO | disclosed |
| US-7727997-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-7683075-B2 | Isoquinoline-3-carboxylic acid amides and pharmaceutical uses thereof | NOVARTIS AG (CH) | 2010-03-23 | — | — | US | disclosed |
| EP-1558610-B1 | SUBSTITUTED AMINOQUINUCLIDINE COMPOUNDS AND THEIR USE AS DELTA-OPIOID RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA NV (BE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070213316-A1 | Compounds that are effective inhibitors of beta-secretase; inhibitors of beta-secretase-mediated cleavage of amyloid precursor proteins; effective inhibitors of A beta production, and/or are effective to reduce amyloid beta deposits or plaques; treatment of disorders such as Alzheimer's Disease | ELAN PHARMACEUTICALS, INC. | 2007-09-13 | — | — | US | disclosed |
| US-20070142428-A1 | Isoquinoline-3-carboxylic acid amides and pharmaceutical uses thereof | NOVARTIS AG (CH) | 2007-06-21 | — | — | US | disclosed |
| EP-1558610-A2 | SUBSTITUTED AMINOQUINUCLIDINE COMPOUNDS AND THEIR USE AS DELTA-OPIOID RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004099206-A1 | ISOQUINOLINE-3-CARBOXYLIC ACID AMIDES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2004-11-18 | — | — | WO | disclosed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | PHARMACIA & UPJOHN COMPANY | 2004-09-02 | — | — | US | disclosed |
| US-20040110789-A1 | Substituted aminoquinuclidine compounds | BOYD ROBERT E (US) | 2004-06-10 | — | — | US | disclosed |
| WO-2004035574-A2 | SUBSTITUTED AMINOQUINUCLIDINE COMPOUNDS AND THEIR USE AS DELTA-OPIOID RECEPTOR LIGANDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-29 | — | — | WO | disclosed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1025109-A1 | BENZOXAZINE DERIVATIVES, PREPARATION AND APPLICATION IN THERAPY | SANOFI-SYNTHELABO (FR) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020633-A1 | BENZOXAZINE DERIVATIVES, PREPARATION AND APPLICATION IN THERAPY | SANOFI-SYNTHELABO (FR) | 1999-04-29 | — | — | WO | disclosed |
| US-5721251-A | INCREASING SECRETION OF GROWTH HORMONE IN HUMANS AND ANIMALS | MERCK & CO., INC. (US) | 1998-02-24 | — | — | US | disclosed |