⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765342 | 0.77 | — | — | |
| SCHEMBL9382652 | 0.74 | CES1 (0.40) | — | |
| SCHEMBL9410349 | 0.72 | — | — | |
| SCHEMBL3194251 | 0.70 | — | — | |
| SCHEMBL5781083 | 0.70 | — | — | |
| SCHEMBL7442391 | 0.65 | — | — | |
| SCHEMBL16106104 | 0.65 | — | — | |
| SCHEMBL2523451 | 0.65 | — | — | |
| SCHEMBL113923 | 0.64 | — | — | |
| SCHEMBL16887409 | 0.64 | PLA2G10 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636955-B | Tetrazolinone compound and use thereof | 住友化学株式会社 | 2018-01-12 | — | — | CN | disclosed |
| US-7666866-B2 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 2010-02-23 | — | — | US | disclosed |
| EP-1819693-B1 | ANTITHROMBOTIC DIAMIDES | LILLY CO ELI (US) | 2009-08-26 | — | — | EP | disclosed |
| US-20090062271-A1 | Antithrombotic Diamides | ELI LILLY AND COMPANY (US) | 2009-03-05 | — | — | US | disclosed |
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0315115-B1 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARM CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| CN-1009553-B | PREPARATION METHOD OF COMPOUNDS OF 5,6-DIHYDRO-4H-CYOCLOPENTADIENE (B) THIOPHENE-6-CARBOXYLIC ACID | LYON INDUSTRAL MEDICINE CO (FR) | 1990-09-12 | — | — | CN | disclosed |
| CN-85106178-A | 5,6 dihydros-4H-cyclopenta (b) thiophene-6-carboxylic acid compound and contain the preparation method of the medicine of these compounds | — | 1987-03-04 | — | — | CN | disclosed |