SCHEMBL3199232

SCHEMBL3199232

CC1=C(C)C(C)=C(c2ccc3ccccc3c2/C=N/c2c(C)cc(C)cc2C)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.37
KMT2A Q03164 10/20 0.37
MEN1 O00255 9/20 0.37
ALDH1A1 P00352 6/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
GAA P10253 8/20 0.36
HCRTR1 O43613 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 2/20 0.35
THRB P10828 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199237 1.00 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3199708 0.85 KMT2A (0.51) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3199716 0.85 KMT2A (0.51) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3213516 0.84 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3213521 0.84 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3211616 0.83 KMT2A (0.38) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3211621 0.83 KMT2A (0.38) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3200981 0.81 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3200977 0.81 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL3211613 0.78 MAPT (0.37) MAPTKMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885KMT2A 2101/4885MEN1 1101/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885KMT2A 2101/4885MEN1 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.