⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxy-6-Methylpyran-2-One SCHEMBL22656780 | 0.93 | CYP3A4 (0.87) | — | |
| 4-Hydroxy-6-Methylpyran-2-One SCHEMBL7254328 | 0.83 | CYP3A4 (0.69) | — | |
| 4-Hydroxy-6-Methylpyran-2-One SCHEMBL30462617 | 0.76 | MEN1 (0.57) | — | |
| SCHEMBL4439220 | 0.75 | — | — | |
| SCHEMBL981128 | 0.74 | — | — | |
| SCHEMBL11619492 | 0.74 | — | — | |
| SCHEMBL31275031 | 0.72 | — | — | |
| SCHEMBL2573803 | 0.71 | CYP3A4 (0.56) | — | |
| SCHEMBL7663185 | 0.70 | — | — | |
| SCHEMBL12464950 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1035 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121202849-B | Coumarin-pyrazole ring hybridization derivative and preparation method and application thereof | NORTHWEST UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| US-20260125689-A1 | Novel Nuclear Localization Sequence Mutant and Method for Improving Biosynthetic Efficiency Using Same | UNIV JIANGNAN (CN) | 2026-05-07 | — | — | US | claimed |
| US-20260085054-A1 | DERIVATIVE OF HISPIDIN FROM SANGHUANGPORUS SANGHUANG, AND PREPARATION METHOD AND USE THEREOF | UNIV CHINA THREE GORGES CTGU (CN) | 2026-03-26 | — | — | US | claimed |
| WO-2025128424-A1 | CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-06-19 | — | — | WO | claimed |
| US-20250197337-A1 | CONVERSION OF TRIACETIC ACID LACTONE TO POTASSIUM SORBATE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-06-19 | — | — | US | claimed |
| CN-119751857-A | Non-isocyanate polyurea and preparation method thereof, water-based non-isocyanate polyurea and preparation method thereof, and anti-corrosion coating, waterproof coating and fireproof coating containing water-based non-isocyanate polyurea and preparation method thereof | 山西省建筑科学研究院集团有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119372225-A | Application of gene pmtA in improving broad-spectrum tolerance of escherichia coli | 上海交通大学 | 2025-01-28 | — | — | CN | claimed |
| CN-116693488-B | Coumarin dye capable of being used for latent fingerprint development and preparation method of fingerprint powder | 青岛科技大学 | 2024-12-20 | — | — | CN | claimed |
| US-20240308950-A1 | BIORENEWABLE SYNTHESIS OF HYDROXY-HEXANOATE ESTERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2024-09-19 | — | — | US | claimed |
| CN-116283761-B | 3-Alkenyl ketone substituted quinoline-2-ketone and green synthesis method thereof | 青岛农业大学 | 2024-06-28 | — | — | CN | claimed |
| US-20060024967-A1 | Polishing composition for noble metals | CABOT MICROELECTRONICS CORPORATION (US) | 2006-02-02 | — | — | US | claimed |
| WO-2004018552-A1 | USE OF COMPOSITIONS CONTAINING 4-HYDROXY-2-PYRONES FOR STABILISING ORGANIC PLASTICS CONTAINING HALOGEN | REAGENS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | WO | claimed |
| CN-1118463-C | Simple synthesis of 6-methyl-4-hydroxy-2-pyrone | UNIV CHINA AGRICULTURAL (CN) | 2003-08-20 | — | — | CN | claimed |
| EP-1324993-A2 | SUBSTITUTED 1,4-THIAZEPINE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2001079187-A2 | SUBSTITUTED 1,4-THIAZEPINE AND ANALOGS AND THEIR USE AS ACTIVATORS OF CASPASES | CYTOVIA, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| CN-1288891-A | Simple synthesis of 6-methyl-4-hydroxy-2-pyrone | CHIAN AGRICULTURAL UNIV (CN) | 2001-03-28 | — | — | CN | claimed |
| US-4570003-A | DEACETYLATION OF DEHYDROACETIC ACID USING AQUEOUS SULFURIC ACID SOLUTION; RATIOS | ROHM AND HAAS COMPANY (US) | 1986-02-11 | — | — | US | claimed |
| EP-0059052-B1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED PYRONE | ROHM AND HAAS COMPANY (US) | 1985-08-07 | — | — | EP | claimed |
| EP-0059052-A1 | Process for the preparation of a substituted pyrone | ROHM AND HAAS COMPANY (US) | 1982-09-01 | — | — | EP | claimed |
| US-3931235-A | FROM THE ALKALIMETAL SALT OF 4-HYDROXY-6-METHYL-2-PYRONE AND A THIOLSULFONATE | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | claimed |