Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 18/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 18/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 18/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 18/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 18/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 18/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 18/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204591 | 0.83 | APP (0.51) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL3209879 | 0.81 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20545519 | 0.81 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20545011 | 0.81 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL7317658 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20545504 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20544603 | 0.80 | HDAC1 (0.68) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20590122 | 0.79 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL20590117 | 0.79 | HDAC1 (0.97) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11033529 | 0.78 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683185-B2 | Histone deacetylase inhibitors | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2010-03-23 | — | — | US | claimed |