⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455796 | 0.78 | — | — | |
| SCHEMBL1661673 | 0.78 | — | — | |
| SCHEMBL1663681 | 0.78 | — | — | |
| SCHEMBL1476768 | 0.76 | — | — | |
| SCHEMBL18576616 | 0.76 | — | — | |
| SCHEMBL15330936 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9143086 | 0.74 | EGLN1 (0.45) | — | |
| SCHEMBL27558661 | 0.65 | — | — | |
| SCHEMBL27907553 | 0.65 | — | — | |
| SCHEMBL242266 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9101662-B2 | Compositions with modulating agents | FOAMIX PHARMACEUTICALS LTD. (IL) | 2015-08-11 | — | — | US | claimed |
| US-8795693-B2 | Compositions with modulating agents | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | claimed |
| EP-2097065-A2 | FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS | Foamix Ltd. (IL) | 2009-09-09 | — | — | EP | claimed |
| WO-2008152444-A2 | FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS | FOAMIX LTD. (US) | 2008-12-18 | — | — | WO | claimed |
| US-20080206159-A1 | Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions | FOAMIX LTD. (IL) | 2008-08-28 | — | — | US | claimed |
| US-9101662-B2 | Compositions with modulating agents | FOAMIX PHARMACEUTICALS LTD. (IL) | 2015-08-11 | — | — | US | disclosed |
| US-8795693-B2 | Compositions with modulating agents | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | disclosed |
| US-20140080140-A1 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS | THE INSTITUTE FOR ETHNOMEDICINE | 2014-03-20 | — | — | US | disclosed |
| US-8541184-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2013-09-24 | — | — | US | disclosed |
| US-8383887-B2 | Methods of using plants containing the gdhA gene | SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2013-02-26 | — | — | US | disclosed |
| US-20100223693-A1 | METHODS OF USING PLANTS CONTAINING THE GDHA GENE | SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2010-09-02 | — | — | US | disclosed |
| US-7670783-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2010-03-02 | — | — | US | disclosed |
| US-4482725-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR | E. R. SQUIBB & SONS, INC. (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0022219-B1 | 5-OXO- AND 5-THIOXOPROLINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.R. Squibb & Sons, Inc. (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4221912-A | Dithio derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4217458-A | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4198515-A | Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4156084-A | Certain dimers of tetrahydropyridine-2-carboxylic acids or pyrroline-2-carboxylic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4154942-A | Certain tetrahydropyridine-2-carboxylic acids and pyrroline-2-carboxylic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4129566-A | Derivatives of dehydrocyclicimino acids | E. R. SQUIBB & SONS, INC. (US) | 1978-12-12 | — | — | US | disclosed |