SCHEMBL3201048

SCHEMBL3201048

NC1CC(N)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.56
SLC6A3 Q01959 4/20 0.56
SLC6A4 P31645 2/20 0.48
KDM1A O60341 10/20 0.47
MAOB P27338 9/20 0.47
KDM1B Q8NB78 2/20 0.46
HTR2A P28223 1/20 0.46
MAOA P21397 7/20 0.42
CYP2C19 P33261 4/20 0.42
CYP2B6 P20813 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 2/20 0.42
LMNA P02545 2/20 0.42
TAAR1 Q96RJ0 2/20 0.42
CYP3A4 P08684 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2C P28335 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30450726 1.00 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4KDM1AMAOB
Hydrochloric Acid SCHEMBL6926090 0.97 SLC6A2 (0.54) SLC6A2SLC6A3SLC6A4KDM1AMAOB
Hydrochloric Acid SCHEMBL6926088 0.97 SLC6A2 (0.54) SLC6A2SLC6A3SLC6A4KDM1AMAOB
Hydrochloric Acid SCHEMBL6929594 0.97 SLC6A2 (0.54) SLC6A2SLC6A3SLC6A4KDM1AMAOB
Hydrochloric Acid SCHEMBL6931517 0.97 SLC6A2 (0.54) SLC6A2SLC6A3SLC6A4KDM1AMAOB
Hydrochloric Acid SCHEMBL6931523 0.97 SLC6A2 (0.54) SLC6A2SLC6A3SLC6A4KDM1AMAOB
SCHEMBL3077728 0.84 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4KDM1AMAOB
SCHEMBL5114376 0.84 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4KDM1AMAOB
SCHEMBL3077730 0.84 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4KDM1AMAOB
SCHEMBL783666 0.84 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0865276-A4 POLYAMINE DERIVATIVES OF 1-AMINOINDAN GILAD GAD (IL) 2003-07-30 EP claimed
EP-0865276-A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN Gilad, Gad (IL) 1998-09-23 EP claimed
US-5646188-A FOR TREATING NEUROTRAUMA TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1997-07-08 US claimed
WO-1997002027-A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1997-01-23 WO claimed
EP-3495349-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2023-06-28 EP disclosed
CN-109195593-A For treating the combination of the LSD1 inhibitor of solid tumor 奥莱松基因组股份有限公司 2019-01-11 CN disclosed
CN-105324359-B Ligand compound, catalyst system for olefin oligomerization, and method for olefin oligomerization using same 株式会社LG化学 2018-01-16 CN disclosed
CN-107074824-A Phthalazine derivatives of formula (I) as PCAF and GCN5 inhibitors for the treatment of cancer 基因泰克公司 2017-08-18 CN disclosed
US-9637508-B2 Ligand compound, catalyst system for olefin oligomerization, and method for olefin oligomerization using the same LG CHEM, LTD. (KR) 2017-05-02 US disclosed
US-20160122371-A1 LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERAZATION, AND METHOD FOR OLEFIN OLIGOMERIZATION USING THE SAME LG CHEM, LTD. (KR) 2016-05-05 US disclosed
EP-2987783-A1 LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND OLEFIN OLIGOMERIZATION METHOD USING SAME LG Chem, Ltd. (KR) 2016-02-24 EP disclosed
CN-105324359-A Ligand compound, catalyst system for olefin oligomerization, and method for olefin oligomerization using same LG CHEMICAL LTD 2016-02-10 CN disclosed
US-20080194535-A1 DIAMINOPROPANE DERIVED MACROCYCLES AS INHIBITORS OF BETA AMYLOID PRODUCTION BRISTOL-MYERS SQUIBB COMPANY 2008-08-14 US disclosed
EP-0865276-A4 POLYAMINE DERIVATIVES OF 1-AMINOINDAN GILAD GAD (IL) 2003-07-30 EP disclosed
EP-0865276-A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN Gilad, Gad (IL) 1998-09-23 EP disclosed
US-5646188-A FOR TREATING NEUROTRAUMA TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1997-07-08 US disclosed
WO-1997002027-A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1997-01-23 WO disclosed
US-4414220-A HUPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1983-11-08 US disclosed
US-4333932-A DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1982-06-08 US disclosed
US-4220650-A HYPOGLYCEMIC PFIZER INC. (US) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194535-A1 DIAMINOPROPANE DERIVED MACROCYCLES AS INHIBITORS OF BETA AMYLOID PRODUCTION APP, BACE1, BACE2 SLC6A2 2683/4885SLC6A3 2132/4885SLC6A4 3791/4885
US-20160122371-A1 LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERAZATION, AND METHOD FOR OLEFIN OLIGOMERIZATION USING THE SAME OXER1, OSTC, OCIAD1 SLC6A2 4681/4885SLC6A3 4479/4885SLC6A4 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.