⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479445 | 1.00 | — | — | |
| SCHEMBL81157 | 1.00 | — | — | |
| SCHEMBL11651946 | 0.82 | — | — | |
| SCHEMBL6293385 | 0.82 | — | — | |
| Phosphine SCHEMBL5401251 | 0.82 | — | — | |
| SCHEMBL1899652 | 0.82 | — | — | |
| SCHEMBL23235911 | 0.71 | — | — | |
| SCHEMBL10364713 | 0.71 | — | — | |
| SCHEMBL1461498 | 0.71 | — | — | |
| SCHEMBL1285 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117046523-A | Method for on-line recovery of activity of deactivated rhodium in propylene hydroformylation catalyst | 万华化学集团股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110872260-B | Method for synthesizing chiral lactam by asymmetric hydrogenation of 2-hydroxypyrazine compound under catalysis of palladium | 中国科学院大连化学物理研究所 | 2021-08-03 | — | — | CN | disclosed |
| CN-110872260-A | Method for synthesizing chiral lactam by asymmetric hydrogenation of 2-hydroxypyrazine compound under catalysis of palladium | 中国科学院大连化学物理研究所 | 2020-03-10 | — | — | CN | disclosed |
| EP-2102182-B1 | CATALYTIC PROCESS FOR ASYMMETRIC HYDROGENATION | BIAL PORTELA & CA SA (PT) | 2014-04-23 | — | — | EP | disclosed |
| US-8546571-B2 | Catalytic hydrogenation of ene-carbamates | BIAL—Portela & C.A., S.A. (PT) | 2013-10-01 | — | — | US | disclosed |
| WO-2012004352-A2 | MESOPOROUS DIPHOSPHINE-TRANSITION METAL COMPLEX CATALYST FOR HYDROFORMYLATION | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2012-01-12 | — | — | WO | disclosed |
| US-20100036127-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2010-02-11 | — | — | US | disclosed |
| EP-2102182-A2 | CATALYTIC PROCESS FOR ASYMMETRIC HYDROGENATION | Bial-Portela & CA, S.A. (PT) | 2009-09-23 | — | — | EP | disclosed |
| EP-2049514-A1 | NITRATE ESTERS OF PIPERIDINES | Speedel Experimenta AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| EP-1621613-B1 | Enzymatic reductions with dihydrogen via metal catalyzed cofactor regeneration | EASTMAN CHEM CO (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1181356-A2 | ENZYMATIC REDUCTIONS WITH DIHYDROGEN VIA METAL CATALYZED COFACTOR REGENERATION | EASTMAN CHEMICAL COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001034612-A2 | CHIRAL PHOSPHINES, TRANSITION METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-2000053731-A2 | ENZYMATIC REDUCTIONS WITH DIHYDROGEN VIA METAL CATALYZED COFACTOR REGENERATION | EASTMAN CHEMICAL COMPANY (US) | 2000-09-14 | — | — | WO | disclosed |
| US-5874639-A | Metal-ligand complex catalyzed processes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-4593011-A | Rhodium complex catalyst | UNION CARBIDE CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0073961-B1 | HYDROFORMYLATION PROCESS USING A RHODIUM COMPLEX CATALYST WITH BIPHOSPHINE MONOXIDE LIGANDS | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4522933-A | Hydroformylation catalyst containing bisphosphine monooxide ligands | UNION CARBIDE CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4491675-A | RHODIUM CATALYZED REACTION | UNION CARBIDE CORPORATION (US) | 1985-01-01 | — | — | US | disclosed |
| US-4400548-A | Hydroformylation process using bisphosphine monooxide ligands | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0073961-A1 | Hydroformylation process using a rhodium complex catalyst with biphosphine monoxide ligands | UNION CARBIDE CORPORATION (US) | 1983-03-16 | — | — | EP | disclosed |