Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206912 | 0.92 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL320182 | 0.88 | S1PR1 (0.66) | S1PR1S1PR3 | |
| SCHEMBL10206913 | 0.88 | S1PR1 (0.66) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL27904557 | 0.87 | S1PR1 (0.65) | S1PR1S1PR3 | |
| SCHEMBL17715217 | 0.83 | S1PR1 (0.65) | S1PR1S1PR3 | |
| SCHEMBL19339937 | 0.81 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL10207208 | 0.81 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL320291 | 0.81 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL319696 | 0.81 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL319532 | 0.81 | S1PR1 (0.65) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590956-B1 | 5-(biphenyl-4-yl)-3-phenyl-1,2,4-oxadiazolyl derivatives as ligands on the sphingosine 1-phosphate (S1P) receptors | MERCK SERONO SA (CH) | 2016-05-04 | — | — | EP | disclosed |
| EP-2590956-A1 | 5-(BIPHENYL-4-YL)-3-PHENYL-1,2,4-OXADIAZOLYL DERIVATIVES AS LIGANDS ON THE SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTORS | Merck Serono S.A. (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004287-A1 | 5-(BIPHENYL-4-YL)-3-PHENYL-1,2,4-OXADIAZOLYL DERIVATIVES AS LIGANDS ON THE SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTORS | MERCK SERONO S.A. (CH) | 2012-01-12 | — | — | WO | disclosed |