SCHEMBL3201657

SCHEMBL3201657

CC(=O)c1c(O)cc(O)c(C=O)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.58
MAPT P10636 1/20 0.58
USP2 O75604 2/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 1/20 0.48
PTGES O14684 3/20 0.46
ALOX5 P09917 2/20 0.46
PTPN1 P18031 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
FFAR1 O14842 2/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ERN1 O75460 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
PRKCI P41743 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048606 0.82 CYP3A4 (0.70) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL30460437 0.82 CYP3A4 (0.70) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL1258932 0.80 CYP3A4 (0.64) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL28679059 0.79 CYP3A4 (0.59) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL31040545 0.79 FFAR1 (0.69) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL10609480 0.78 CYP3A4 (0.52) CYP3A4MAPTUSP2PTGESPTPN1
Acetic Acid SCHEMBL9753023 0.76 CYP3A4 (0.58) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL21061225 0.76 CYP3A4 (0.58) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL29353199 0.76 CYP3A4 (0.58) CYP3A4MAPTUSP2MEN1KMT2A
SCHEMBL11152281 0.74 CYP3A4 (0.51) CYP3A4MAPTUSP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111205196-B Phenol AB ring structure compound and preparation method and application thereof 中国科学院昆明植物研究所 2021-04-02 CN disclosed
CN-111205196-A Phenol AB ring structure compound and preparation method and application thereof 中国科学院昆明植物研究所 2020-05-29 CN disclosed
US-20100028469-A1 Extracts of Cranberry and Methods of Using Thereof HERBALSCIENCE GROUP, LLC (US) 2010-02-04 US disclosed