SCHEMBL3201760

SCHEMBL3201760

CCCCCC1(O)CC(=O)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 17/20 0.48
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17161347 0.84 CYP19A1 (0.40) CYP19A1
SCHEMBL1828884 0.78 TSHR (0.54) CYP19A1TSHRNPSR1
Hydrochloric Acid SCHEMBL17139431 0.76 TSHR (0.52) CYP19A1TSHRNPSR1
SCHEMBL6077915 0.76 CYP19A1 (0.51) CYP19A1TSHRNPSR1
SCHEMBL27666457 0.73 CYP19A1 (0.49) CYP19A1TSHRNPSR1
SCHEMBL11435977 0.71 CYP19A1 (0.45) CYP19A1TSHRNPSR1
SCHEMBL5690991 0.71 CYP19A1 (0.49) CYP19A1TSHRNPSR1
SCHEMBL27637547 0.70 CYP19A1 (0.42) CYP19A1TSHRNPSR1
SCHEMBL18529897 0.70 CYP19A1 (0.44) CYP19A1TSHRNPSR1
SCHEMBL570644 0.70 CYP19A1 (0.48) CYP19A1TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107619433-B Glycopeptide derivative and pharmaceutically acceptable salt, preparation method and application thereof 上海来益生物药物研究开发中心有限责任公司 2023-03-17 CN claimed
CN-107619432-B Glycopeptide derivative and pharmaceutically acceptable salt, preparation method and application thereof 上海来益生物药物研究开发中心有限责任公司 2023-03-17 CN claimed
CN-107619432-A Glycopeptide derivant and its pharmaceutically acceptable salt, preparation method and application 上海来益生物药物研究开发中心有限责任公司 2018-01-23 CN claimed
CN-107619433-A Glycopeptide derivant and its pharmaceutically acceptable salt, preparation method and application 上海来益生物药物研究开发中心有限责任公司 2018-01-23 CN claimed
US-4354950-A ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES TEXACO INC. (US) 1982-10-19 US claimed
EP-3915614-A1 CRACK RESISTANT MEMBER Daicel Corporation (JP) 2021-12-01 EP disclosed
CN-112239511-A Hydrogenated block copolymer, hydrogenated block copolymer composition, and molded article 旭化成株式会社 2021-01-19 CN disclosed
CN-107619433-A Glycopeptide derivant and its pharmaceutically acceptable salt, preparation method and application 上海来益生物药物研究开发中心有限责任公司 2018-01-23 CN disclosed
CN-107619432-A Glycopeptide derivant and its pharmaceutically acceptable salt, preparation method and application 上海来益生物药物研究开发中心有限责任公司 2018-01-23 CN disclosed
EP-1481043-B1 HYDROXY AROMATIC MANNICH BASE CONDENSATION PRODUCTS AND THE USE THEREOF AS SOOT DISPERSANTS IN LUBRICATING OIL COMPOSITIONS INFINEUM INT LTD (GB) 2017-11-29 EP disclosed
US-7790808-B2 Method for producing a thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-07 US disclosed
CN-100430369-C Hydroxy aromatic mannich base condensation products and use thereof as soot dispersants in lubricating oil compsns. INFINEUM INT LTD (GB) 2008-11-05 CN disclosed
EP-0357217-A2 Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-03-07 EP disclosed
EP-0356010-A1 Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-28 EP disclosed
US-4828742-A OIL AND FUEL ADDITIVES EXXON CHEMICAL PATENTS, INC. (US) 1989-05-09 US disclosed
US-4820432-A FROM LACTONE, AMINE, ALDEHYDE, HYDROXYARYLAMINE, AND HYDROCARBYL SUBSTITUTED UNSATURATED DICARBOXYLIC ACID EXXON CHEMICAL PATENTS INC. (US) 1989-04-11 US disclosed
EP-0304175-A1 Lactone-modified, Mannich base dispersant additives useful in oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1989-02-22 EP disclosed
EP-0302643-A1 Lactone-modified mannich base dispersant additives useful in oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1989-02-08 EP disclosed
US-4354950-A ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES TEXACO INC. (US) 1982-10-19 US disclosed
US-4354950-A ANTISLUDGE AGENTS FOR INTERNAL COMBUSTION ENGINES TEXACO INC. (US) 1982-10-19 US disclosed