SCHEMBL3202190

SCHEMBL3202190

CC(C)(C)C1=C(c2ccc3ccccc3c2/C=N/Nc2ccccc2)CC=C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 13/20 0.50
KMT2A Q03164 13/20 0.50
KDM4E B2RXH2 7/20 0.50
MAPT P10636 6/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
ALDH1A1 P00352 5/20 0.50
HTT P42858 3/20 0.50
HPGD P15428 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
RRM1 P23921 2/20 0.41
RAB9A P51151 8/20 0.41
NPC1 O15118 6/20 0.41
TDP1 Q9NUW8 5/20 0.41
MITF O75030 2/20 0.41
KLF5 Q13887 1/20 0.41
GAA P10253 5/20 0.39
POLB P06746 1/20 0.36
LMNA P02545 5/20 0.35
SENP7 Q9BQF6 2/20 0.35
CASP3 P42574 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202202 1.00 MEN1 (0.50) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3208310 0.85 MEN1 (0.53) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3208312 0.85 MEN1 (0.53) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3200964 0.83 MEN1 (0.50) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3200973 0.83 MEN1 (0.50) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3201490 0.79 MAPT (0.43) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3201482 0.79 MAPT (0.43) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3205394 0.79 ERN1 (0.41) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL3207534 0.77 MEN1 (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2
SCHEMBL3207543 0.77 MEN1 (0.54) MEN1KMT2AKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MEN1 1101/4885KMT2A 2101/4885KDM4E 4084/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MEN1 1101/4885KMT2A 2101/4885KDM4E 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.