Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 10/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.38 |
| ▸ | CDK1 | P06493 | 7/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.38 |
| ▸ | CDK4 | P11802 | 6/20 | 0.38 |
| ▸ | CCND1 | P24385 | 6/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 6/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202275 | 1.00 | CDK2 (0.38) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1482941 | 0.85 | CDK2 (0.36) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1240783 | 0.84 | CDK2 (0.38) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1238529 | 0.84 | CDK2 (0.38) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1238524 | 0.84 | CDK2 (0.38) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1240824 | 0.83 | CDK2 (0.38) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1241316 | 0.82 | CCNE1 (0.40) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1241338 | 0.82 | CDK2 (0.37) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL2606465 | 0.81 | CDK2 (0.43) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL1240409 | 0.81 | CDK2 (0.41) | CDK2CCNE2CCNE1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318778-B2 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2012-11-27 | — | — | US | disclosed |
| US-20100041711-A1 | Urea Glucokinase Activators | NOVO NORDISK A/S (DK) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041711-A1 | Urea Glucokinase Activators | GCK, GCKR, HK2 | CDK2 381/4885CCNE2 2292/4885CCNE1 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.