Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.94 |
| ▸ | CHKA | P35790 | 1/20 | 0.94 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HBB | P68871 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL17966130 | 0.97 | CHRM5 (0.89) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL189 | 0.97 | — | — | |
| SCHEMBL8664726 | 0.97 | CHRM5 (1.00) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Bromide SCHEMBL393565 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL4405649 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Phosphine SCHEMBL23270013 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Bromide SCHEMBL1542160 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Bromide SCHEMBL393564 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| Hydrochloric Acid SCHEMBL9013636 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 | |
| SCHEMBL2277093 | 0.94 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457338-B | Alpha-selective hydroboration reaction method of electron-deficient olefin | 中国科学技术大学 | 2022-01-14 | — | — | CN | claimed |
| CN-112457338-A | Alpha-selective hydroboration reaction method of electron-deficient olefin | 中国科学技术大学 | 2021-03-09 | — | — | CN | claimed |
| CN-107188811-B | A method of reduction thioamide analog compound | 阿里生物新材料（常州）有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-107188811-A | A kind of method for reducing thioamide analog compound | 阿里化学(常州)有限公司 | 2017-09-22 | — | — | CN | claimed |
| EP-0680484-B1 | OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEXES | NISSAN CHEMICAL IND LTD (JP) | 1998-08-19 | — | — | EP | claimed |
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3146027-B1 | LUBRICANT COMPOSITION COMPRISING HYDROXY FUNCTIONALIZED ASHLESS ADDITIVE | LUBRIZOL CORP (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023176487-A1 | METHOD FOR PRODUCING L-PENICILLAMINE | 株式会社カネカ | 2023-09-21 | — | — | WO | disclosed |
| CN-114516815-A | Controllable defluorination deuteration method for polyfluoroamide | 中国科学技术大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-112457338-B | Alpha-selective hydroboration reaction method of electron-deficient olefin | 中国科学技术大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-112457338-B | Alpha-selective hydroboration reaction method of electron-deficient olefin | 中国科学技术大学 | 2022-01-14 | — | — | CN | disclosed |
| US-5739347-A | REDUCING AGENTS FOR DECARBONYLATION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5663348-A | REDUCTION OF DIKETONE WITH AMINOALKOXYBORANE COMPLEX TO FORM DIALCOHOL ESTER COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| CN-1116850-A | Optically active beta-aminoalkoxyborane complexes | NISSAN CHEMICAL IND LTD (JP) | 1996-02-14 | — | — | CN | disclosed |
| EP-0680484-A1 | OPTICALLY ACTIVE $g(b)-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017079-A1 | OPTICALLY ACTIVE β-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-08-04 | — | — | WO | disclosed |
| US-5332801-A | For blends | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5120800-A | Boriding with borane compound having at least one boron-hydrogen bond and oxidizing | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0451819-A2 | Process for preparing modified-polyphenylene ether | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | TP53, TP53BP1, MDM2 | CHRM5 4637/4885CHKA 2009/4885MAPT 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.