⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467683 | 0.76 | — | — | |
| SCHEMBL27266167 | 0.74 | — | — | |
| SCHEMBL9619662 | 0.74 | — | — | |
| SCHEMBL2691290 | 0.74 | FFAR3 (0.35) | — | |
| SCHEMBL2560001 | 0.72 | — | — | |
| SCHEMBL1449044 | 0.71 | — | — | |
| SCHEMBL510845 | 0.71 | — | — | |
| SCHEMBL7021597 | 0.71 | — | — | |
| SCHEMBL301825 | 0.71 | — | — | |
| SCHEMBL9154262 | 0.71 | FFAR3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-3097105-B1 | 2-(1,3,4-OXADIAZOL-2-YL)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LTD (IN) | 2018-12-19 | — | — | EP | disclosed |
| US-9845323-B2 | 2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1 ]octane derivatives and their use as antibacterial agents | WOCKHARDT LIMITED (IN) | 2017-12-19 | — | — | US | disclosed |
| US-9822115-B2 | Nitrogen containing compounds and their use as antibacterial agents | WOCKHARDT LIMITED (IN) | 2017-11-21 | — | — | US | disclosed |
| US-9657022-B2 | 7-OXO-1,6-diazabicyclo[3.2.1]octane derivatives and their use as antibacterial agents | WOCKHARDT LIMITED (IN) | 2017-05-23 | — | — | US | disclosed |
| EP-2855456-B1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| US-20170044159-A1 | 7-OXO-1,6-DIAZABICYCLO[3.2.1 ]OCTANE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LIMITED (IN) | 2017-02-16 | — | — | US | disclosed |
| US-20160355516-A1 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | WOCKHARDT LIMITED (IN) | 2016-12-08 | — | — | US | disclosed |
| EP-3097106-A1 | 7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Wockhardt Limited (IN) | 2016-11-30 | — | — | EP | disclosed |
| EP-3097104-A2 | NITROGEN CONTAINING COMPOUNDS AND THEIR USE | Wockhardt Limited (IN) | 2016-11-30 | — | — | EP | disclosed |
| US-20070135385-A1 | Methyl indoxam; obesity; dietectics; antidiabetic agents; insulin resistance; non-insulin dependent diabetes; glucose intolerance; hypercholesterolemia; hypertriglyceridemia; anticholesterol agents; metabolic disorders; foods;bioavailability; side effect reduction | ILYPSA, INC. | 2007-06-14 | — | — | US | disclosed |
| WO-2007056279-A2 | PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056280-A1 | INDOLE COMPOUNDS HAVING C4-ACIDIC SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056275-A2 | INDOLE COMPOUNDS HAVING C4-AMIDE SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056281-A2 | MULTIVALENT INDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2002016304-A1 | METHOD FOR PRODUCING ALPHA FLUOROMALONIC ACID DIALKYL ESTERS | BAYER CROPSCIENCE AG (DE) | 2002-02-28 | — | — | WO | disclosed |
| EP-0597329-B1 | Process for the preparation of alpha-fluor-beta dicarbonyle compounds | BAYER AG (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0597329-A2 | Process for the preparation of alpha-fluor-beta dicarbonyle compounds | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993013062-A1 | HALOGENATED TETRAENYL PROSTAGLANDIN DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5177251-A | Cytoprotective, antisecretory, side effect reduction | G. D. SEARLE & CO. (US) | 1993-01-05 | — | — | US | disclosed |