⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624066 | 1.00 | — | — | |
| SCHEMBL9078870 | 0.95 | — | — | |
| SCHEMBL8751713 | 0.93 | — | — | |
| SCHEMBL3178458 | 0.90 | — | — | |
| SCHEMBL12458394 | 0.90 | — | — | |
| SCHEMBL5495733 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL5498982 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7900380 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7616318 | 0.87 | — | — | |
| SCHEMBL29481681 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508428-A | Spiro compound | DAIICHI PHAMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | claimed |
| JP-5286933-A | — | — | None | — | — | JP | disclosed |
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-6031102-A | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5587386-A | BACTERICIDES, MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| JP-H05286933-A | SALT OF AZASPIROOCTANE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1993-11-02 | — | — | JP | disclosed |