SCHEMBL3203788

SCHEMBL3203788

C(=NNc1ccccc1)c1c(C2C(c3ccccc3)=Cc3ccccc32)ccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 12/20 0.51
KMT2A Q03164 12/20 0.51
MAPT P10636 6/20 0.51
KDM4E B2RXH2 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
RAB9A P51151 8/20 0.42
NPC1 O15118 7/20 0.42
GAA P10253 6/20 0.42
RRM1 P23921 2/20 0.42
TDP1 Q9NUW8 3/20 0.42
MITF O75030 2/20 0.42
KLF5 Q13887 1/20 0.42
POLB P06746 2/20 0.39
NOX1 Q9Y5S8 1/20 0.35
LMNA P02545 2/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3203782 1.00 MEN1 (0.51) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL3192390 0.85 MEN1 (0.52) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL3192394 0.85 MEN1 (0.52) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL3212071 0.83 KMT2A (0.48) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL3212078 0.83 KMT2A (0.48) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL3212231 0.81 MAPT (0.34) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL3212228 0.81 MAPT (0.34) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL3211796 0.80 MEN1 (0.59) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL3211792 0.80 MEN1 (0.59) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL3206543 0.80 MAPT (0.46) MEN1KMT2AMAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MEN1 1101/4885KMT2A 2101/4885MAPT 2641/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MEN1 1101/4885KMT2A 2101/4885MAPT 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.