Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844174 | 0.93 | CHRNA7 (0.48) | CHRNA7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL5399730 | 0.86 | MAP4K4 (0.45) | CHRNA7CHRM1CHRM2TLR7 | |
| Hydrochloric Acid SCHEMBL5417675 | 0.85 | MAP4K4 (0.44) | CHRNA7CHRM1CHRM2TLR7 | |
| SCHEMBL1542353 | 0.85 | CHRM1 (0.49) | CHRNA7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL1542354 | 0.85 | CHRM1 (0.49) | CHRNA7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL1542520 | 0.84 | CHRNA7 (0.73) | CHRNA7 | |
| SCHEMBL1542518 | 0.84 | CHRNA7 (0.73) | CHRNA7 | |
| SCHEMBL14459864 | 0.82 | CHRNA7 (0.55) | CHRNA7CHRM1CHRM2TLR7 | |
| SCHEMBL13479859 | 0.81 | CHRM1 (0.49) | CHRNA7CHRM1CHRM2TLR7 | |
| SCHEMBL14338732 | 0.81 | CHRM1 (0.49) | CHRNA7CHRM1CHRM2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242668-A1 | Dimeric Azacyclic Compounds and Their Use | NEUROSEARCH A/S (DK) | 2008-10-02 | — | — | US | claimed |
| EP-1713809-A1 | DIMERIC AZACYCLIC COMPOUNDS AND THEIR USE | NEUROSEARCH A/S (DK) | 2006-10-25 | — | — | EP | claimed |
| WO-2005075479-A1 | DIMERIC AZACYCLIC COMPOUNDS AND THEIR USE | NEUROSEARCH A/S (DK) | 2005-08-18 | — | — | WO | claimed |
| US-7674899-B2 | Dimeric azacyclic compounds and their use | NEUROSEARCH A/S (DK) | 2010-03-09 | — | — | US | disclosed |
| US-20080242668-A1 | Dimeric Azacyclic Compounds and Their Use | NEUROSEARCH A/S (DK) | 2008-10-02 | — | — | US | disclosed |
| EP-1713809-A1 | DIMERIC AZACYCLIC COMPOUNDS AND THEIR USE | NEUROSEARCH A/S (DK) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075479-A1 | DIMERIC AZACYCLIC COMPOUNDS AND THEIR USE | NEUROSEARCH A/S (DK) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242668-A1 | Dimeric Azacyclic Compounds and Their Use | CHRNA6, CHRNA5, CHRNA10 | CHRNA7 5/4885CHRM1 24/4885CHRM2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.