SCHEMBL3205055

SCHEMBL3205055

CC1=CCC(c2ccc3ccccc3c2C#N)=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 5/20 0.38
MAPT P10636 4/20 0.38
CYP1A2 P05177 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
GAA P10253 2/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
LMNA P02545 1/20 0.35
PRMT5 O14744 4/20 0.33
WDR77 Q9BQA1 4/20 0.33
CYP2C19 P33261 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
ALOX15 P16050 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 2/20 0.32
PIM1 P11309 2/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3211227 0.82 KDM4E (0.33) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3192926 0.77 KDM4E (0.37) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3208536 0.74 KDM4E (0.38) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3207699 0.74 ERN1 (0.44) KDM4EALDH1A1MAPTCYP1A2KMT2A
SCHEMBL3198152 0.74 KDM4E (0.37) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3210197 0.74 CA1 (0.39) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3191514 0.73 NCEH1 (0.32) CYP1A2MEN1KMT2ATSHRCYP2A6
SCHEMBL3213029 0.73 CYP1A2 (0.31) CYP1A2TSHRCYP2A6
SCHEMBL3199679 0.73 NCEH1 (0.41) KDM4EALDH1A1MAPTCYP1A2MEN1
SCHEMBL3213378 0.72 TSHR (0.42) KDM4EALDH1A1CYP1A2GAACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 KDM4E 4084/4885ALDH1A1 1229/4885MAPT 2641/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 KDM4E 4084/4885ALDH1A1 1229/4885MAPT 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.