SCHEMBL3205643

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.65

▸	NPY1R	P25929	9/20	0.65

▸	NPY5R	Q15761	8/20	0.65

▸	NPY2R	P49146	5/20	0.63

▸	KISS1R	Q969F8	4/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31437677	0.88	NPY4R (0.61)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30866924	0.88	NPY4R (0.56)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31258159	0.87	NPY4R (0.61)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL24059390	0.86	NPY4R (0.55)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31018699	0.85	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31433247	0.85	NPY4R (0.59)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31180467	0.85	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30866935	0.84	NPY4R (0.62)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30866923	0.84	NPY4R (0.62)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31273124	0.84	NPY4R (0.66)	NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100047762-A1	METHOD TO MONITOR DRUG EFFICACY IN DIABETIC PATIENTS USING AN ASSAY FOR 1,5-ANHYDRO-D-GLUCITOL	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2010-02-25	—	—	US	disclosed