Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038817 | 1.00 | NPC1 (0.69) | NPC1RAB9ATDP1PKMLCK | |
| SCHEMBL29643958 | 0.88 | NPC1 (0.59) | NPC1RAB9ATDP1PKMPOLB | |
| SCHEMBL28623980 | 0.88 | NPC1 (0.59) | NPC1RAB9ATDP1PKMPOLB | |
| SCHEMBL14825173 | 0.84 | POLB (0.56) | NPC1RAB9ATDP1POLBMAPK1 | |
| SCHEMBL29531380 | 0.83 | NPC1 (0.79) | NPC1RAB9APKMPOLBGRM4 | |
| SCHEMBL12437777 | 0.83 | NPC1 (0.79) | NPC1RAB9APKMPOLBGRM4 | |
| SCHEMBL31501093 | 0.82 | NPC1 (0.49) | NPC1RAB9APOLBMAPK1L3MBTL1 | |
| SCHEMBL21620972 | 0.82 | NPC1 (1.00) | NPC1RAB9AGRM4HDAC6LMNA | |
| SCHEMBL19476175 | 0.82 | NPC1 (0.52) | NPC1RAB9ATDP1PKMPOLB | |
| SCHEMBL22204798 | 0.81 | NPC1 (0.51) | NPC1RAB9ATDP1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4686757-A1 | INHIBITORS OF EXPRESSION AND/OR FUNCTION | e-therapeutics PLC (GB) | 2026-02-04 | — | — | EP | disclosed |