SCHEMBL3208280

SCHEMBL3208280

CC(C)c1ccc2sc3ccccc3c(=O)c2c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
MAPT P10636 7/20 0.52
ALDH1A1 P00352 4/20 0.52
POLB P06746 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
GAA P10253 2/20 0.52
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
HPGD P15428 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
LMNA P02545 3/20 0.41
BLM P54132 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27980566 0.84 MAPT (0.54) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL156858 0.84 MAPT (0.50) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL20448784 0.82 MAPT (0.49) MAOAMAOBMAPTALDH1A1POLB
Phosphine SCHEMBL28097474 0.82 MAPT (0.49) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL27756701 0.82 MAPT (0.46) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL27760689 0.81 MAPT (0.50) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL52045 0.81 MAPT (0.50) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL29359906 0.81 MAPT (0.50) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL29675381 0.81 MAPT (0.50) MAOAMAOBMAPTALDH1A1POLB
SCHEMBL28872510 0.81 MAPT (0.58) MAOAMAOBMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2044137-B1 COMPOSITION THAT CAN BE POLYMERIZED AND/OR CROSSLINKED WHEN IRRADIATED BY CATIONIC AND/OR RADICAL ROUTE VENCOREX FRANCE (FR) 2015-03-04 EP disclosed
US-8436066-B2 Compositions polymerizable/crosslinkable by cationic/radical irradiation VENCOREX FRANCE (FR) 2013-05-07 US disclosed
US-20100035003-A1 COMPOSITIONS POLYMERIZABLE/CROSSLINKABLE BY CATIONIC/RADICAL IRRADIATION PERSTORP FRANCE (FR) 2010-02-11 US disclosed
EP-2044137-A1 COMPOSITION THAT CAN BE POLYMERIZED AND/OR CROSSLINKED WHEN IRRADIATED BY CATIONIC AND/OR RADICAL ROUTE PERSTORP TOLONATES FRANCE (FR) 2009-04-08 EP disclosed
CN-101219423-A Kitchen garbage drying processor FUJI PHOTO FILM CO LTD (JP) 2008-07-16 CN disclosed
EP-1406956-B1 SURFACE TREATMENT OF PLASTIC MATERIAL WITH AN ORGANIC POLYMERISABLE AND/OR CROSSLINKABLE COMPOSITION HAVING REACTIVE FUNCTIONS RHODIA CHIMIE SA (FR) 2008-03-26 EP disclosed
WO-2008012281-A1 COMPOSITION THAT CAN BE POLYMERIZED AND/OR CROSSLINKED WHEN IRRADIATED BY CATIONIC AND/OR RADICAL ROUTE PERSTORP TOLONATES FRANCE (FR) 2008-01-31 WO disclosed
US-6929863-B2 Surface treatment of plastic material with an organic polymerizable and/or crosslinkable composition having reactive functions RHODIA SERVICES (FR) 2005-08-16 US disclosed
US-6911235-B2 Plastic material surface treatment with a polymerizable and/or crosslinkable organic composition having reactive functions RHODIA CHIMIE (FR) 2005-06-28 US disclosed
EP-1406957-A1 PLASTIC MATERIAL SURFACE TREATMENT WITH A POLYMERISABLE AND/OR CROSSLINKABLE ORGANIC COMPOSITION HAVING REACTIVE FUNCTIONS RHODIA CHIMIE (FR) 2004-04-14 EP disclosed
US-20030211338-A1 Plastic material surface treatment with a polymerisable and/or crosslinkable organic composition having reactive functions RHODIA CHIMIE (FR) 2003-11-13 US disclosed
US-20030199661-A1 Surface treatment of plastic material with an organic polymerisable and/or crosslinkable composition having reactive functions RHODIA SERVICES (FR) 2003-10-23 US disclosed
WO-2003010257-A1 PRESSURE-SENSITIVE ADHESIVE SILICONE COMPOSITIONS, PREPARATION METHODS AND USES THEREOF RHODIA CHIMIE (FR) 2003-02-06 WO disclosed
WO-2002092716-A1 PRESSURE-SENSITIVE ADHESIVE SILICONE COMPOSITIONS, METHOD FOR PREPARING SAME AND USES THEREOF RHODIA CHIMIE (FR) 2002-11-21 WO disclosed
EP-1237982-A1 RADIATION POLYMERISABLE AND/OR CROSSLINKABLE ADHESIVE FOR PLASTIC BASED ON MATRIX WITH REACTIVE FUNCTIONS RHODIA CHIMIE (FR) 2002-09-11 EP disclosed
WO-2001062834-A1 SURFACE TREATMENT OF PLASTIC MATERIAL WITH AN ORGANIC POLYMERISABLE AND/OR CROSSLINKABLE COMPOSITION HAVING REACTIVE FUNCTIONS RHODIA CHIMIE (FR) 2001-08-30 WO disclosed
WO-2001062835-A1 PLASTIC MATERIAL SURFACE TREATMENT WITH A POLYMERISABLE AND/OR CROSSLINKABLE ORGANIC COMPOSITION HAVING REACTIVE FUNCTIONS RHODIA CHIMIE (FR) 2001-08-30 WO disclosed
WO-2001036512-A1 RADIATION POLYMERISABLE AND/OR CROSSLINKABLE ADHESIVE FOR PLASTIC BASED ON MATRIX WITH REACTIVE FUNCTIONS RHODIA CHIMIE (FR) 2001-05-25 WO disclosed
EP-0970405-A1 UE RHODIA CHIMIE (FR) 2000-01-12 EP disclosed
WO-1998043134-A1 (E.G. INK OR VARNISH) COMPOSITION POLYMERISABLE AND/OR CROSSLINKABLE UNDER RADIATION EXPOSURE BY CATIONIC AND/OR RADICAL PROCESS, WITH AN ORGANIC MATRIX BASE, OF A DILUENT AND A PHOTOINITIATOR RHODIA CHIMIE (FR) 1998-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035003-A1 COMPOSITIONS POLYMERIZABLE/CROSSLINKABLE BY CATIONIC/RADICAL IRRADIATION XRCC6, XRCC5, ERCC1 MAOA 1435/4885MAOB 2195/4885MAPT 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.