Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 19/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209039 | 1.00 | PIM1 (0.60) | PIM1CLK1DYRK2MEN1LMNA | |
| SCHEMBL13496549 | 0.90 | PIM1 (0.55) | PIM1CLK1DYRK2MAPT | |
| SCHEMBL2835682 | 0.83 | MAPT (0.48) | PIM1CLK1DYRK2MEN1LMNA | |
| SCHEMBL2835685 | 0.83 | MAPT (0.48) | PIM1CLK1DYRK2MEN1LMNA | |
| SCHEMBL31653941 | 0.75 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL14115819 | 0.71 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL7243809 | 0.71 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL29696854 | 0.71 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL28595477 | 0.70 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL3227542 | 0.69 | CCR1 (0.50) | PIM1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149557-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-02-03 | — | — | EP | claimed |
| EP-2149557-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-02-03 | — | — | EP | disclosed |
| EP-2149557-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-02-03 | — | — | EP | disclosed |
| WO-2010010148-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010148-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-01-28 | — | — | WO | disclosed |