Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409113 | 0.89 | MEN1 (0.40) | MEN1KMT2ATDP1 | |
| SCHEMBL27397491 | 0.87 | — | — | |
| SCHEMBL3151340 | 0.85 | MEN1 (0.47) | MEN1KMT2ATDP1 | |
| SCHEMBL555524 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL1280066 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL6885374 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL297814 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL149623 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| Perfluorocyclobutane SCHEMBL10391737 | 0.79 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL10538153 | 0.78 | MEN1 (0.35) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198869-B1 | TREHALOSE FOR THE TREATMENT OR PREVENTION OF VASOSPASM | NEXT 21 K K (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-8283337-B2 | Therapeutic or prophylactic agent for vasoconstriction | NEXT21 K.K. (JP) | 2012-10-09 | — | — | US | disclosed |
| EP-2198869-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR VASOCONSTRICTION | Next 21 K.K. (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20100035837-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR VASOCONSTRICTION | NEXT21 K.K. (JP) | 2010-02-11 | — | — | US | disclosed |