SCHEMBL320975

SCHEMBL320975

Oc1c(Br)c[c]cc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5462449 0.85
SCHEMBL4050934 0.81
SCHEMBL28711764 0.81
SCHEMBL17133959 0.67
SCHEMBL4032984 0.67
SCHEMBL7235469 0.67
SCHEMBL458414 0.67
SCHEMBL702714 0.65
SCHEMBL28582635 0.65 CA1 (0.35)
SCHEMBL1192985 0.65 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586272-A Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技股份有限公司 2024-02-23 CN claimed
CN-116761598-A Antiviral use of FABP4 modulating compounds 新月生物科学 2023-09-15 CN claimed
CN-116648445-A Methods for treating or preventing chronic kidney disease 安索治疗公司 2023-08-25 CN claimed
CN-112979661-B Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技股份有限公司 2022-05-17 CN claimed
US-20210353631-A1 1,4-Benzoxazines for the Treatment of Cancers and Other Neurodegenerative Diseases Neugeneron LLC 2021-11-18 US claimed
CN-112979661-A Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技有限公司 2021-06-18 CN claimed
CN-107759588-B Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative 江苏新元素医药科技有限公司 2020-10-23 CN claimed
CN-111615515-A Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技有限公司 2020-09-01 CN claimed
EP-3050908-B1 COPOLYCARBONATE AND COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-04 EP claimed
CN-106432229-A Compounds for treating or preventing hyperuricemia or gout 江苏新元素医药科技有限公司 2017-02-22 CN claimed
EP-1228059-B1 NOVEL CYCLOPROPANES AS CGRP ANTAGONISTS, MEDICAMENTS CONTAINING SAID COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF BOEHRINGER INGELHEIM PHARMA (DE) 2005-08-03 EP claimed
US-20040192729-A1 Carboxylic acids and the esters thereof, pharmaceutical compositions thereto and processes for the preparation thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-09-30 US claimed
WO-2004063171-A1 N- (1-BENZYL-2-OXO-2- (1-PIPERAZINYL) ETHYL) -1-PIPERIDINCARBOXAMID-DERIVATIVES AND RELATED COMPOUNDS USE AS CGRP-ANTAGONISTS FOR TREATING A HEADACHE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-07-29 WO claimed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 EP claimed
EP-0347766-B1 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments THOMAE GMBH DR K (DE) 1994-05-25 EP claimed
US-5068325-A Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics KARL THOMAE GMBH (DE) 1991-11-26 US claimed
US-4931512-A REACTING POLY(CYCLIC IMINOETHER) WITH POLYOLS OR POLYAMINES, ACID CATALYST; CURABLE TEIJIN LIMITED (JP) 1990-06-05 US claimed
US-4910265-A Poly(cyclic iminoether) and an acid catalyst TEIJIN LIMITED (JP) 1990-03-20 US claimed
EP-0347766-A2 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments Dr. Karl Thomae GmbH (DE) 1989-12-27 EP claimed
EP-0273368-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1988-07-06 EP claimed