SCHEMBL320976

SCHEMBL320976

O=C=NCC(N=C=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.42
CYP2C19 P33261 2/20 0.40
SRC P12931 1/20 0.34
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
GABBR2 O75899 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32
HTR2A P28223 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28234866 0.98 MIF (0.41) MIFCYP2C19SRCNOS3NOS2
SCHEMBL28219163 0.95 MIF (0.39) MIFCYP2C19SRCNOS3NOS2
SCHEMBL28219540 0.90 MIF (0.36) MIFCYP2C19
SCHEMBL2025269 0.90 MIF (0.30) MIF
SCHEMBL28501975 0.90 FFAR1 (0.39) MIFCYP2C19
SCHEMBL2139577 0.87 MIF (0.50) MIFCYP2C19
SCHEMBL2139583 0.87 MIF (0.59) MIFCYP2C19SRCNOS3NOS2
SCHEMBL28322061 0.83 MIF (0.31) MIFCYP2C19
SCHEMBL4640624 0.82 MIF (0.46) MIFCYP2C19SRCNOS3NOS2
SCHEMBL28907856 0.81 PYCR1 (0.33) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114806360-B Waterproof material 江苏凯伦建材股份有限公司 2022-12-13 CN claimed
CN-113696366-A Polyurethane activated micro powder and preparation method thereof, polyurethane soft foam and preparation method and application thereof 青岛科技大学 2021-11-26 CN claimed
CN-108586060-B Functional composite coated controlled-release fertilizer with polyolefin wax as base coat and production method thereof 山东农业大学 2021-08-13 CN claimed
CN-112538153-A High-solid-content aqueous polyurethane prepolymer for glass fibers, film-forming agent and preparation method 重庆国际复合材料股份有限公司 2021-03-23 CN claimed
CN-108034350-B Spray-type damping material 青岛沙木新材料有限公司 2020-08-28 CN claimed
CN-106752838-B A kind of polyurethane sealant silane coupling agent and preparation method thereof 山东北方现代化学工业有限公司 2019-11-08 CN claimed
CN-110204679-A A kind of preparation method of modified environment-friendly aqueous polyurethane and its polyurethane of preparation 齐鲁工业大学 2019-09-06 CN claimed
CN-110072388-A Composition comprising polyurethane microcapsules containing cinmethylin 巴斯夫农业公司 2019-07-30 CN claimed
CN-108299613-B A kind of antimicrobial form anion aqueous polyurethane resin and preparation method thereof 合肥科天水性科技有限责任公司 2019-07-26 CN claimed
CN-110041465-A A kind of mono dispersed micrograde elastic microsphere powder and its preparation method and application 广州五行材料科技有限公司 2019-07-23 CN claimed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US claimed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 EP claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010155-A Hydrophilic film CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed
US-4424306-A DIISOCYANATE, PRIMARY DIAMINE NIPPON ZEON CO., LTD. (JP) 1984-01-03 US claimed
EP-0083232-A1 Aqueous compositions comprising blocked isocyanate crosslinking agent FORD MOTOR COMPANY LIMITED (GB) 1983-07-06 EP claimed
US-4321350-A Process for the catalytic setting of polyurethane molding compositions GAMBRO DIALYSATOREN KG (DE) 1982-03-23 US claimed