⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465 | 0.79 | — | — | |
| SCHEMBL27680412 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22092309 | 0.77 | — | — | |
| SCHEMBL27458087 | 0.77 | — | — | |
| SCHEMBL27436100 | 0.77 | — | — | |
| SCHEMBL28017203 | 0.75 | — | — | |
| SCHEMBL29074033 | 0.71 | — | — | |
| SCHEMBL28216966 | 0.71 | — | — | |
| SCHEMBL27784683 | 0.71 | — | — | |
| SCHEMBL28198102 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683082-B2 | 3-(5-p-tolyl-[1,2,4]oxadiazol-3-yl)-benzoic acid; translation of mRNA is allowed to continue past a nonsense mutation point, resulting in full length protein; genetic disorders; testing whether a compound increases activity of a protein encoded by an mRNA that contains a premature stop codon | PTC THERAPEUTICS, INC. (US) | 2010-03-23 | — | — | US | disclosed |