⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051111 | 0.86 | — | — | |
| SCHEMBL12652081 | 0.77 | — | — | |
| SCHEMBL29306897 | 0.77 | — | — | |
| SCHEMBL12613658 | 0.77 | — | — | |
| SCHEMBL12966848 | 0.77 | — | — | |
| SCHEMBL6063703 | 0.75 | — | — | |
| SCHEMBL18155283 | 0.75 | — | — | |
| SCHEMBL22021048 | 0.75 | — | — | |
| SCHEMBL18879937 | 0.75 | — | — | |
| SCHEMBL4291619 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101151246-B | 1-benzylindole-2-carboxamide derivatives | ORGANON NV | 2011-04-13 | — | — | CN | disclosed |
| US-7671080-B2 | 1-benzylindole-2-carboxamide derivatives | N.V. ORGANON (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080280923-A1 | 1-Benzylindole-2-Carboxamide Derivatives | N.V. ORGANON (NL) | 2008-11-13 | — | — | US | disclosed |
| CN-101151246-A | 1-benzylindole-2-carboxamide derivatives | ORGANON NV (NL) | 2008-03-26 | — | — | CN | disclosed |
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |