SCHEMBL321365

SCHEMBL321365

OCCc1[c]cc[c]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9731765 0.86
SCHEMBL1931320 0.85
SCHEMBL4285823 0.80
SCHEMBL209994 0.76
SCHEMBL9556084 0.76
SCHEMBL919191 0.74
SCHEMBL1499438 0.73
SCHEMBL4522847 0.70
SCHEMBL248845 0.70
SCHEMBL14776814 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2515842-A2 DYEING AND/OR BLEACHING COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE L'Oréal (FR) 2012-10-31 EP disclosed
US-8092553-B2 Composition for the oxidation dyeing of keratin fibers comprising para-aminophenol, dipropylene glycol and at least one additional dye precursor L'OREAL S.A. (FR) 2012-01-10 US disclosed
US-8012220-B2 Specific monocationic monochromophoric compounds of hydrazone type comprising a 2-, 4-pyridinium or 2-, 4-quinolinium unit, synthesis thereof, dye compositions containing them, and method for dyeing keratin fibres L'OREAL S.A. (FR) 2011-09-06 US disclosed
WO-2011076603-A2 DYEING AND/OR BLEACHING COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE L'OREAL (FR) 2011-06-30 WO disclosed
EP-2032540-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT L'Oreal (FR) 2009-03-11 EP disclosed
WO-2008034650-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT L'OREAL (FR) 2008-03-27 WO disclosed
US-6679923-B2 HAIR DYEING FORMULATION CONTAINING PYRAZOLIN-4,5-DIONES AND AT LEAST ONE AROMATIC PRIMARY AMINE ENABLES THE DYEING OF KERATIN FIBERS WITHOUT AND OXIDIZING AGENT IN SHADES WHICH ARE STRONG, VARIED, RESISTANT AND LESS SELECTIVE L'OREAL S.A. (FR) 2004-01-20 US disclosed
US-6669933-B2 For oxidatively coloring hair in twelve minutes or less REVLON CONSUMER PRODUCTS CORPORATION 2003-12-30 US disclosed
WO-2002089748-A2 METHOD AND COMPOSITIONS FOR COLORING HAIR REVLON CONSUMER PRODUCTS CORPORATION (US) 2002-11-14 WO disclosed
US-6464732-B2 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-10-15 US disclosed
US-5964898-A OXIDATION HAIR DYES L'OREAL (FR) 1999-10-12 US disclosed
US-5599353-A APPLYING TO HAIR THE OXIDATION DYE PRECURSOR, COUPLERS, OXIDIZING AGENT, DEVELOPING COLOR IN ALKALINE, ACIDIC OR NEUTRAL MEDIUM; RESISTANCE TO LIGHT, WASHES, BAD WEATHER AND PERSPIRATION L'OREAL (FR) 1997-02-04 US disclosed
EP-0688558-A2 Composition for dyeing keratinous fibres comprising 2-(beta-hydroxyethyl)-paraphenylene-diamine, 2-methylresorcin and resorcin L'OREAL (FR) 1995-12-27 EP disclosed
US-5187167-A Antitumor agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-16 US disclosed
US-5081124-A Amino acid and polyamino acid derivatives, inhibitors of thymidylate synthetase IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-01-14 US disclosed
US-4992550-A Thymidylate synthetase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-02-12 US disclosed