Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CD69 | Q07108 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743332 | 0.90 | POLB (0.62) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL830740 | 0.89 | KMT2A (0.60) | L3MBTL1SMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL1145948 | 0.87 | KMT2A (0.62) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL11556734 | 0.84 | PTPN1 (0.49) | L3MBTL1SMN1; SMN2KMT2AALDH1A1PTPN1 | |
| SCHEMBL2059383 | 0.84 | POLB (0.58) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL654774 | 0.83 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL29966790 | 0.83 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL28044483 | 0.82 | KMT2A (0.53) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| SCHEMBL27918156 | 0.81 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2POLBGLAKMT2A | |
| Hydrochloric Acid SCHEMBL16239152 | 0.81 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2POLBGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590642-A2 | PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE | Alkon, Daniel L. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012006525-A2 | PKC ACTIVATORS AND ANTICOAGULANT IN REGIMEN FOR TREATING STROKE | ALKON DANIEL L (US) | 2012-01-12 | — | — | WO | disclosed |