Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973124 | 0.80 | GAA (0.73) | TSHRGLAKDM4EGAAKMT2A | |
| SCHEMBL3218307 | 0.80 | SMN1; SMN2 (0.51) | TSHRKMT2AMGLLALDH1A1 | |
| SCHEMBL3222628 | 0.79 | MAPK14 (0.51) | MGLL | |
| SCHEMBL12911161 | 0.78 | TSHR (0.69) | TSHRGLAKDM4EPARP10GAA | |
| SCHEMBL315088 | 0.78 | TSHR (0.72) | TSHRGLAKDM4EPARP10GAA | |
| SCHEMBL314589 | 0.78 | TSHR (0.75) | TSHRGLAKDM4EGAAKMT2A | |
| SCHEMBL774880 | 0.76 | KDM1A (0.57) | — | |
| SCHEMBL3221724 | 0.76 | POLB (0.49) | TSHRKMT2AMGLLALDH1A1 | |
| SCHEMBL13423695 | 0.76 | PDK2 (0.53) | MGLL | |
| SCHEMBL3218302 | 0.76 | PDK2 (0.53) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |