⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367496 | 0.97 | KDM1A (0.31) | — | |
| SCHEMBL6258654 | 0.97 | — | — | |
| SCHEMBL3224853 | 0.92 | — | — | |
| SCHEMBL9647720 | 0.78 | KDM1A (0.34) | — | |
| SCHEMBL9647725 | 0.78 | KDM1A (0.34) | — | |
| SCHEMBL7609745 | 0.78 | KDM1A (0.34) | — | |
| SCHEMBL28419841 | 0.76 | KDM1A (0.33) | — | |
| SCHEMBL2010366 | 0.76 | KDM1A (0.33) | — | |
| SCHEMBL8183372 | 0.75 | — | — | |
| SCHEMBL8183376 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748841-B | Method for catalyzing asymmetric synthesis of chiral beta-aminoketone derivative | 浙江工业大学 | 2021-06-01 | — | — | CN | claimed |
| CN-109748841-A | A method of catalysis asymmetric syntheses chiral beta-aminoketone derivative | 浙江工业大学 | 2019-05-14 | — | — | CN | claimed |
| CN-111032751-B | Polymer film, film-like laminate, and method for producing polymer film | 琳得科株式会社 | 2022-10-28 | — | — | CN | disclosed |
| CN-109748841-B | Method for catalyzing asymmetric synthesis of chiral beta-aminoketone derivative | 浙江工业大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109748841-A | A method of catalysis asymmetric syntheses chiral beta-aminoketone derivative | 浙江工业大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-104884536-B | Coating compositions for food and beverage containers | PPG工业俄亥俄公司 | 2017-11-14 | — | — | CN | disclosed |
| US-20160060280-A1 | Remote Assembly of Targeted Nanoparticles Using H-Phosphonate -ENE/-YNE Hydrophosphonylation Reactions | MALLINCKRODT LLC (US) | 2016-03-03 | — | — | US | disclosed |
| US-9216225-B2 | Remote assembly of targeted nanoparticles using H-phosphate ENE/-YNE hydrophosphonylation reactions | MALLINCKRODT LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-8575167-B2 | Spiro compounds having stearoyl-CoA desaturase action | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20130066098-A1 | Remote Assembly of Targeted Nanoparticles using H-Phosphate ENE/-YNE Hydrophosphonylation Reactions | MALLINCKRODT LLC (US) | 2013-03-14 | — | — | US | disclosed |
| CN-102712587-A | Novel ethane diamine hepcidin antagonists | VIFOR INT AG | 2012-10-03 | — | — | CN | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0778821-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1997-06-18 | — | — | EP | disclosed |
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | disclosed |
| EP-0752421-A1 | Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists | ZENECA LIMITED (GB) | 1997-01-08 | — | — | EP | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |
| WO-1996006822-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1996-03-07 | — | — | WO | disclosed |
| WO-1996003380-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1996-02-08 | — | — | WO | disclosed |
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |