⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216652 | 1.00 | — | — | |
| SCHEMBL13491839 | 0.93 | — | — | |
| SCHEMBL7962658 | 0.93 | — | — | |
| SCHEMBL13491862 | 0.93 | — | — | |
| SCHEMBL13491931 | 0.92 | — | — | |
| SCHEMBL7959629 | 0.91 | — | — | |
| SCHEMBL13491925 | 0.91 | — | — | |
| SCHEMBL7964579 | 0.90 | — | — | |
| SCHEMBL13491866 | 0.88 | — | — | |
| SCHEMBL13491952 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118711-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION | 2018-05-03 | — | — | US | disclosed |
| US-20180118711-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION | 2018-05-03 | — | — | US | disclosed |
| US-9783521-B2 | PDE10 inhibitors and related compositions and methods | OMEROS CORPORATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783521-B2 | PDE10 inhibitors and related compositions and methods | OMEROS CORPORATION (US) | 2017-10-10 | — | — | US | disclosed |
| EP-2310016-B1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORP (US) | 2017-10-04 | — | — | EP | disclosed |
| EP-2310016-B1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORP (US) | 2017-10-04 | — | — | EP | disclosed |
| US-20140038951-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140038951-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-8377930-B2 | PDE10 inhibitors and related compositions and methods | OMEROS CORPORATION (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377930-B2 | PDE10 inhibitors and related compositions and methods | OMEROS CORPORATION (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377930-B2 | PDE10 inhibitors and related compositions and methods | OMEROS CORPORATION (US) | 2013-02-19 | — | — | US | disclosed |
| WO-2010017236-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20100035872-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100035872-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100035872-A1 | PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS | OMEROS CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |