Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294368 | 0.98 | CYP1A2 (0.52) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15337622 | 0.98 | CYP1A2 (0.52) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Fluoride SCHEMBL30329871 | 0.96 | CYP1A2 (0.50) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL28065444 | 0.96 | CYP1A2 (0.50) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL28676450 | 0.94 | CYP1A2 (0.48) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL28676451 | 0.94 | CYP1A2 (0.48) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Bromide SCHEMBL28435885 | 0.94 | CYP1A2 (0.58) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| Fluoride SCHEMBL29251853 | 0.92 | CYP1A2 (0.47) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15508580 | 0.92 | CYP1A2 (0.60) | CYP1A2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL292866 | 0.92 | S1PR1 (0.54) | CYP1A2S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116408151-A | Noble metal catalyst for hydrochlorination of acetylene as well as preparation method and application thereof | 鄂尔多斯市瀚博科技有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-116408151-A | Noble metal catalyst for hydrochlorination of acetylene as well as preparation method and application thereof | 鄂尔多斯市瀚博科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-114146726-A | High-dispersion ruthenium-based catalyst and preparation method and application thereof | 内蒙古鄂尔多斯电力冶金集团股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-107803225-A | It is a kind of to be used to produce ruthenium catalyst of vinyl chloride and preparation method thereof | 浙江工业大学 | 2018-03-16 | — | — | CN | disclosed |
| CN-107744836-A | A kind of preparation method and applications of load-type ion liquid catalyst | 浙江工业大学 | 2018-03-02 | — | — | CN | disclosed |
| US-20150158020-A1 | SYNTHESIS OF ZEOLITES USING AN ORGANOAMMONIUM COMPOUND | UOP LLC | 2015-06-11 | — | — | US | disclosed |
| US-8593714-B2 | Composite electrode and electrolytes comprising nanoparticles and resulting devices | AJJER, LLC (US) | 2013-11-26 | — | — | US | disclosed |
| US-20100039690-A1 | Composite electrode and electrolytes comprising nanoparticles and resulting devices | AJJER LLC (US) | 2010-02-18 | — | — | US | disclosed |