Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.79 |
| ▸ | LPAR1 | Q92633 | 10/20 | 0.79 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.71 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.71 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.71 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.71 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | PRKCG | P05129 | 1/20 | 0.58 |
| ▸ | PRKCB | P05771 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | PRKCH | P24723 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | PRKCI | P41743 | 1/20 | 0.58 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.58 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172379 | 1.00 | LPAR3 (0.79) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL5610918 | 1.00 | LPAR3 (0.79) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL5610920 | 1.00 | LPAR3 (0.79) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL10566328 | 0.92 | LPAR3 (0.68) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL4979389 | 0.91 | LPAR3 (0.76) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL2814732 | 0.89 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL15477507 | 0.89 | LPAR3 (0.77) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL5055004 | 0.89 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL10896195 | 0.89 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL4948840 | 0.89 | LPAR3 (0.77) | LPAR3LPAR1LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082846-A | Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis | SANDOZ LTD. (CH) | 1992-01-21 | — | — | US | claimed |
| EP-0092190-B1 | PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-24 | — | — | EP | claimed |
| CN-115175735-A | Antiviral compounds | 吉利德科学公司 | 2022-10-11 | — | — | CN | disclosed |
| WO-2010008852-A2 | METHODS OF TREA FING ΛΛD METHODS OF DIAGNOSING AN IMMUNOPROLIFERATIVE DISORDER | TAIGA BIOTECHNOLOGIES, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-5082846-A | Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis | SANDOZ LTD. (CH) | 1992-01-21 | — | — | US | disclosed |
| US-5082846-A | Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis | SANDOZ LTD. (CH) | 1992-01-21 | — | — | US | disclosed |
| US-5082846-A | Use of the R-(+)-isomer of 2-methoxy-3-octadecyloxy-propanol-(1)-phosphoric acid, monocholine ester in treating multiple sclerosis | SANDOZ LTD. (CH) | 1992-01-21 | — | — | US | disclosed |
| US-5010067-A | Triglyceride-water emulsion pharmaceutical vehicles | SANDOZ PHARMACEUTICALS CORP. (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0224925-A2 | Phosphorous compounds and medicines containing them | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1987-06-10 | — | — | EP | disclosed |
| US-4585762-A | ANTITUMOR AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |