⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347241 | 0.92 | — | — | |
| SCHEMBL27887961 | 0.89 | TSHR (0.35) | — | |
| SCHEMBL14151313 | 0.88 | — | — | |
| SCHEMBL28002820 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL1098581 | 0.81 | — | — | |
| SCHEMBL11847078 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL9669445 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL28142962 | 0.80 | TSHR (0.42) | — | |
| SCHEMBL27759030 | 0.79 | — | — | |
| SCHEMBL8878250 | 0.78 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109173756-A | A kind of quaternized polypyrrole modified cation exchange membrane of bromine alkane and its preparation and application | 浙江工业大学 | 2019-01-11 | — | — | CN | claimed |
| CN-109173756-B | Bromine alkyl quaternized polypyrrole modified cation exchange membrane and preparation and application thereof | 浙江工业大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-110066278-A | Fused tricyclic class compound and its application in drug | 广东东阳光药业有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109173756-A | A kind of quaternized polypyrrole modified cation exchange membrane of bromine alkane and its preparation and application | 浙江工业大学 | 2019-01-11 | — | — | CN | disclosed |
| EP-3260515-A1 | POLISHING COMPOSITION | Fujimi Incorporated (JP) | 2017-12-27 | — | — | EP | disclosed |
| CN-104250363-B | Polyisocyanate composition | 旭化成株式会社 | 2017-01-11 | — | — | CN | disclosed |
| EP-3048152-A1 | POLISHING COMPOSITION | Fujimi Incorporated (JP) | 2016-07-27 | — | — | EP | disclosed |
| CN-105713213-A | Molecule assembling-based preparation method of polypyrrolone membrane | 江西师范大学 | 2016-06-29 | — | — | CN | disclosed |
| EP-2142531-B1 | BENZIMIDAZOLE CANNABINOID AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-08 | — | — | EP | disclosed |
| CN-103553945-B | Alkoxy compounds for disease treatment | ACUCELA INC | 2015-01-07 | — | — | CN | disclosed |
| CN-101889017-B | Alkoxy compounds for the treatment of diseases | ACUCELA INC | 2013-11-27 | — | — | CN | disclosed |
| US-8193369-B2 | Benzimidazole cannabinoid agonists | JANSSEN PHARMACEUTICA NV (BE) | 2012-06-05 | — | — | US | disclosed |
| CN-101516887-B | Thiazole pyrazolopyrimidines as crf1 receptor antagonists | LILLY CO ELI | 2011-11-02 | — | — | CN | disclosed |
| CN-101889017-A | Alkoxy compounds for the treatment of diseases | ACUCELA INC | 2010-11-17 | — | — | CN | disclosed |
| CN-101790518-A | Derivatives of 1-oxo-1, 2-dihydroisoquinoline-5-carboxamides and of 4-oxo-3, 4-dihydroquinazoline-8-carboxamides, preparation thereof and therapeutic use thereof | SANOFI AVENTIS | 2010-07-28 | — | — | CN | disclosed |
| CN-101679355-A | benzimidazole cannabinoid agonists | JANSSEN PHARMACEUTICA NV | 2010-03-24 | — | — | CN | disclosed |
| US-20100041702-A1 | BENZIMIDAZOLE CANNABINOID AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-18 | — | — | US | disclosed |
| EP-2142531-A1 | BENZIMIDAZOLE CANNABINOID AGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2010-01-13 | — | — | EP | disclosed |
| CN-101516887-A | Thiazole pyrazolopyrimidines as CRF1 receptor antagonists | LILLY CO ELI (US) | 2009-08-26 | — | — | CN | disclosed |
| WO-2008119694-A1 | BENZIMIDAZOLE CANNABINOID AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2008-10-09 | — | — | WO | disclosed |