SCHEMBL3217498

SCHEMBL3217498

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)CCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.58
▸ NPY5R Q15761 9/20 0.58
▸ NPY1R P25929 9/20 0.58
▸ NPY2R P49146 6/20 0.58
▸ TFPI P10646 1/20 0.58
▸ KISS1R Q969F8 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870837 0.97 NPY4R (0.62) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL31277748 0.90 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL30522316 0.90 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL31430937 0.88 NPY4R (0.68) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL31437674 0.87 NPY4R (0.57) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL29789581 0.86 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL30601532 0.86 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL31437671 0.86 NPY4R (0.57) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL30522315 0.86 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RTFPI
SCHEMBL30618025 0.86 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962697-B2 Bioreponsive polymers INTERFACE BIOLOGICS INC. (CA) 2015-02-24 — — US disclosed
US-20100041771-A1 Bioreponsive Polymers INTERFACE BIOLOGICS, INC. 2010-02-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041771-A1 Bioreponsive Polymers PEPD, PREP, DNPEP NPY4R 1902/4885NPY5R 2786/4885NPY1R 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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