SCHEMBL3218192

SCHEMBL3218192

C#CCc1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21490856 0.92 HRH1 (0.42)
SCHEMBL27295191 0.78 HRH1 (0.55)
SCHEMBL38655688 0.78 HRH1 (0.55)
Water SCHEMBL9578432 0.77 MAPT (0.50)
SCHEMBL4701110 0.77
SCHEMBL348980 0.77
SCHEMBL365933 0.77
SCHEMBL6545761 0.77
SCHEMBL8710864 0.77
SCHEMBL8710867 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP claimed
CN-116903612-A Diaryl methane derivative containing indolizine and preparation method and application thereof 江西师范大学 2023-10-20 CN claimed
CN-115650980-A Oxindole compound and preparation method and application thereof 江西师范大学 2023-01-31 CN claimed
CN-114163436-A Diarylmethane derivative containing indolizine and preparation method and application thereof 江西师范大学 2022-03-11 CN claimed
CN-114105978-A Oxindole compound and preparation method and application thereof 江西师范大学 2022-03-01 CN claimed
CN-110291673-A The pyridine. sulfur trioxide complex compound of electrolyte components as high-tension battery group 巴斯夫欧洲公司 2019-09-27 CN claimed
EP-2934135-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP claimed
EP-2648731-B1 CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V ABBVIE DEUTSCHLAND (DE) 2017-01-25 EP claimed
EP-1753512-B1 TETRAHYDROPYRIDOTHIOPHENES NYCOMED GMBH (DE) 2008-07-09 EP claimed
EP-1562955-B1 QUINAZOLINE DERIVATIVES AS SRC TYROSINE KINASE INHIBITORS ASTRAZENECA AB (SE) 2008-02-27 EP claimed
EP-1218353-B1 QUINAZOLINE DERIVATIVES ASTRAZENECA UK LTD (GB) 2007-10-17 EP claimed
EP-1227859-B1 NEUROPHILIN LIGANDS FOR TREATING OCULAR CONDITIONS ALCON INC (CH) 2006-08-09 EP claimed
EP-1140828-B1 3-AZABICYCLO¬3.1.0|HEXANE DERIVATIVES AS OPIATE RECEPTORS LIGANDS PFIZER LTD (GB) 2006-08-09 EP claimed
EP-1226126-B1 PYRIMIDINE DERIVATIVES ASTRAZENECA AB (SE) 2005-01-05 EP claimed
EP-0786455-B1 IMIDAZOLE DERIVATIVE SHIONOGI & CO (JP) 2003-12-03 EP claimed
EP-0719779-B1 SUBSTITUTED THIAZOLO [3,2-ALPHA]AZEPINE DERIVATIVE EISAI CO LTD (JP) 2003-11-19 EP claimed
EP-1206444-B1 COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY MORPHOCHEM AG (DE) 2003-11-12 EP claimed
EP-0949259-B1 N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME NIKKEN CHEMICALS CO LTD (JP) 2001-06-20 EP claimed
EP-0612321-B1 PYRIDO PYRIDAZINONE AND PYRIDAZINTHIONE COMPOUNDS WITH PDE IV INHIBITING ACTIVITY SYNTEX INC (US) 1999-08-25 EP claimed
EP-0584223-B1 NOVEL IMMUNOSUPPRESSIVE COMPOUNDS VERTEX PHARMA (US) 1999-08-11 EP claimed